Personal profile
Biography
Dr Rachelle Irwin is a Lecturer in Genomic Medicine and a Principal Investigator (PI) at the Centre for Genomic Medicine in the School of Biomedical Science, Ulster University. Dr Irwin’s research is focused on epigenetic epidemiology, with interest in understanding the role of epigenetics in human health and disease.
Dr Irwin graduated from Ulster University with BSc Hons Biomedical Science (1st Class), proceeding to undertake her PhD in the Transcriptional Regulation and Epigenetics research group which examined maternal programming of neural gene methylation and transcription. Following her PhD, Dr Irwin was appointed as a BBRSC/ERSC-funded Research Associate in the Genomic Medicine Research Group at Ulster University. During this period, she worked on an interdisciplinary project relating to a longitudinal randomized controlled trial investigating the epigenetic effects of folic acid supplementation on children's psychosocial development in the second and third trimester of pregnancy.
Dr Irwin was appointed as a Lecturer at Ulster University in 2019 where she assumed the role of Course Director for the BSc Hons Biology degree, which she led through recent successful accreditation by the Royal Society of Biology. She teaches on a range of modules at undergraduate and postgraduate level. In addition to her teaching endeavours, Dr Irwin is actively involved in supervising postgraduate students and outreach activity.
To date, Dr. Irwin has published more than 17 scientific papers in top-ranked scientific journals across a range of disciplines. She is a Fellow of the Higher Education Academy, a member of the Royal Society of Biology and a member of the Genetics Society. Dr Irwin is an editorial board member for Frontiers in Genetics, Frontiers in Endocrinology and the Journal of Childhood and Adolescent Trauma.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
-
SDG 2 Zero Hunger
-
SDG 3 Good Health and Well-being
-
SDG 4 Quality Education
-
SDG 10 Reduced Inequalities
-
SDG 11 Sustainable Cities and Communities
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
-
Maternal adiposity and DNA methylation of TfR2 and HJV genes in early pregnancy: mediating role of inflammation and consequences for iron status
Demirdjian, S. P., Irwin, R. E., Thompson, P. D., Mulhern, M. S., Kerr, M. A., Ledwidge, M., Rahman, K. L., Conway, C., Rodriguez, E. P. & McCann, M. T., 30 Apr 2026, In: The Journal of nutrition. 156, 4, p. 1-11 11 p., 101393.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Downloads (Pure) -
Exercise-Epigenetic Axis: Metabolic Alignment to Oxidative Stress and Redox Status
Davison, G., Mohammed, A., Irwin, R. E., Lees-Murdock, D. & Walsh, C., 26 Nov 2025, (Published online) Exercise, Epigenetics and Human Health. Gao, F. & Zhang, X. (eds.). Switzerland, Vol. 15. p. 115-136 21 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
-
Assessing the efficacy of active learning to support student performance across undergraduate programmes in Biomedical Science
Lees-Murdock, D., Khan, D., Irwin, R. E., Graham, J., Hinch, V., O'Hagan, B. & McClean, S., 4 Mar 2024, (Published online) In: British Journal of Biomedical Science. 81, p. 1-8 8 p., 12148.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Link opens in a new tab Citations (Scopus)107 Downloads (Pure) -
Cognitive benefits of folic acid supplementation during pregnancy track with epigenetic changes at an imprint regulator
Hilman, L., Ondičová, M., Caffrey, A., Clements, M., Conway, C., Ward, M., Pentieva, K., Irwin, R. E., McNulty, H. & Walsh, C. P., 16 Dec 2024, In: BMC Medicine. 22, 1, 579 (2024).Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Link opens in a new tab Citations (Scopus)29 Downloads (Pure) -
Senescence Signatures Predict Hospitalization Risk and Severity in COVID-19 Patients
Lynch, S. M., McLarnon, T., Cooper, E., McDaid, D., Guo, G., McLaughlin, J., McGilligan, V. E., Watterson, S., Shukla, P., Zhang, S.-D., Bucholc, M., English, A., Freeman, L., Irwin, R. E., Peace, A., O’Kane, M., Kelly, M., Bhavsar, M., Murray, E. K. & Gibson, D. S. & 3 others, , 23 Sept 2024, (Published online) In: Aging Biology. 2, 1, p. 1-14 14 p., 20240035.Research output: Contribution to journal › Article › peer-review
Open AccessFile160 Downloads (Pure)
Datasets
-
Supporting data for "CandiMeth: Powerful yet simple visualization and quantification of DNA methylation at candidate genes"
Thursby, S.-J. (Creator), Lobo, D. (Creator), Mc Nulty, H. (Creator), Pentieva, K. (Creator), Zhang, S.-D. (Creator), Irwin, R. (Creator) & Walsh, C. (Creator), GigaDB, 20 May 2020
DOI: 10.5524/100753
Dataset
File
Prizes
-
NI Science Festival 2024: Genomic Healthcare in Practice
Lees-Murdock, D. (Organiser), Irwin, R. (Participant), Stafford, C. (Participant) & O'Neill, L. (Participant)
Feb 2024Activity: Participating in or organising an event › Organising a conference, workshop, ...
-
NI Science Festival 2022 'A Wee Bit of Science'
Lees-Murdock, D. (Participant), Hinch, V. (Organiser) & Irwin, R. (Organiser)
18 Feb 2022Activity: Participating in or organising an event › Participating in a conference, workshop, ...
Press/Media
-
Minister hails pioneering Ulster University research in Genomic Medicine
Lees-Murdock, D., Gault, V. & Irwin, R.
28/03/24
1 item of Media coverage
Press/Media: Research
Profiles
-
Pearl Mussel Ecological Analytics & Resource-integrated Land-use Modelling and Action Plan
Irwin, R. (PI), Lees-Murdock, D. (CoI) & Arnscheidt, J. (CoI)
Department of Agriculture, Environment & Rural Affairs (DAERA) of Northern Ireland (UK)
1/04/26 → 31/03/30
Project: Research
-
Role of riboflavinin epigenetic modulation of hypertension
Lees-Murdock, D. (PI), Hughes, C. (CoI), Ward, M. (CoI) & Irwin, R. (CoI)
Northern Ireland Chest Heart and Stroke
1/05/22 → 1/03/24
Project: Research
-
Integrity and inheritance of genome methylation
Walsh, C. (PI) & Irwin, R. (CoI)
31/03/17 → 31/12/19
Project: Research