Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 4 Quality Education -
SDG 5 Gender Equality -
SDG 9 Industry, Innovation, and Infrastructure -
SDG 10 Reduced Inequalities
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Collaborations and top research areas from the last five years
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An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer's disease- associated Aβ oligomers.
Bomfim, T. R., Forny-Germano, L., Sathler, L. B., Brito-Moreira, J., Houzel, J.-C., Decker, H., Silverman, M. A., Kazi, H., Melo, H. M., McClean, P., Holscher, C., Arnold, S. E., Talbot, K., Klein, W. L., Munoz, D. P., Ferreira, S. T. & De Felice, F. G., 2012, In: The Journal of clinical investigation. 122, 4, p. 1339-53Research output: Contribution to journal › Article › peer-review
Open Access786 Link opens in a new tab Citations (Scopus) -
The diabetes drug Liraglutide prevents degenerative processes in a mouse model of Alzheimer's disease.
McClean, P., Parthsarathy, V., Faivre, E. & Holscher, C., 1 May 2011, In: Journal of Neuroscience. 31, 17, p. 6587-6594Research output: Contribution to journal › Article › peer-review
Open Access657 Link opens in a new tab Citations (Scopus) -
GIP receptor antagonism reverses obesity, insulin resistance, and associated metabolic disturbances induced in mice by prolonged consumption of high-fat diet
McClean, P., Irwin, N., Cassidy, R. S., Holst, J. J., Gault, V. & Flatt, P., Dec 2007, In: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 293, 6, p. E1746-E1755Research output: Contribution to journal › Article › peer-review
Open Access228 Link opens in a new tab Citations (Scopus) -
Sustained high-fat diet modulates inflammation, insulin signalling and cognition in mice and a modified xenin peptide ameliorates neuropathology in a chronic high-fat model
Denver, P., Gault, V. A. & McClean, P. L., 15 Apr 2018, In: Diabetes, Obesity and Metabolism. 20, 5, p. 1166-1175 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile65 Link opens in a new tab Citations (Scopus)118 Downloads (Pure) -
Distinguishing normal brain aging from the development of Alzheimer's disease: inflammation, insulin signaling and cognition
Denver, P. & McClean, P., 23 Aug 2018, In: Neural Regeneration Research. 13, 10, p. 1719 1730 p.Research output: Contribution to journal › Article › peer-review
72 Link opens in a new tab Citations (Scopus)
Datasets
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Multimorbidity in the UK Biobank and its change over time
Watterson, S. (Creator), Shukla, P. (Contributor) & Mc Clean, P. (Contributor), Ulster University, 12 Nov 2021
DOI: 10.21251/5dc06676-a5e9-4312-81f0-b3e1b0e00fe3
Dataset
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Prizes
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Collaborative Award for Teaching Excellence (CATE)
McClean, P. (Recipient), Kelly, C. (Recipient), Atkinson, S. (Recipient), Bjourson, T. (Recipient), Duddy, W. (Recipient), Duguez, S. M. (Recipient), Gibson, D. (Recipient), Matchett, K. (Recipient), McDowell, A. (Recipient), Mc Gilligan, V. (Recipient), Murray, E. (Recipient), Shukla, P. (Recipient), Rai, T. S. (Recipient), Watterson, S. (Recipient) & Zhang, S.-D. (Recipient), 3 Oct 2024
Prize: Honorary award
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Distinguished Collaborative Education Excellence Fellowship
McClean, P. (Recipient), Kelly, C. (Recipient), Gibson, D. (Recipient), Mc Gilligan, V. (Recipient), Murray, E. (Recipient), Atkinson, S. (Recipient), Watterson, S. (Recipient), McDowell, A. (Recipient), Duguez, S. M. (Recipient), Duddy, W. (Recipient), Shukla, P. (Recipient), Matchett, K. (Recipient), Rai, T. S. (Recipient) & Zhang, S.-D. (Recipient), 7 Jun 2023
Prize: Honorary award
Profiles
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PoC Stage 3 (Vasimmune Compound 1 (VIC-1) An Orally Available Immunomodulatory Polysaccharide for Alzheimer’s disease therapy)
McClean, P. (PI) & Lynch, O. (CoI)
5/05/25 → 5/11/27
Project: Research
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PoC Stage 3 (Vasimmune Compound 1 (VIC-1) An Orally Available Immunomodulatory Polysaccharide for Alzheimer's disease therapy)
McClean, P. (PI) & Lynch, O. (CoI)
5/05/25 → 5/11/27
Project: Research
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iMPROVE
Gibson, D. (PI), Courtenay, A. (CoI), Kelly, C. (CoI), Murray, E. (CoI), Condell, J. (CoI), Dubras, L. (CoI), McClean, P. (CoI), Shukla, P. (CoI), Zhang, S.-D. (CoI) & McGilligan, V. (CoI)
1/03/25 → 28/02/29
Project: Research
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Investigating the role of the NLRP3 inflammasome and metalloproteinases in neuroinflammatory disease.
McGilligan, V. (PI), Gibson, D. (CoI), Murray, E. (CoI) & McClean, P. (CoI)
1/09/24 → 31/08/27
Project: Research
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Comprehensive and personalized assessment of acute coronary syndrome by multiomic approach and artificial intelligence strategy
Watterson, S. (PI), Kelly, C. (CoI), McClean, P. (CoI), Zhang, S.-D. (CoI), Rai, T. S. (CoI) & McGilligan, V. (CoI)
Horizon Europe - UKRI Guarantee via JeS
1/01/23 → 31/12/26
Project: Research