Neil Tanday – Research output — Ulster University

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Cromore Road, Coleraine Campus
BT52 1SA Coleraine
United Kingdom

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Research activity per year

20 Article
3 Review article

20 results

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2024
[ P³ ] PP, a stable, long‐acting pancreatic polypeptide analogue, evokes weight lowering and pancreatic beta‐cell‐protective effects in obesity‐associated diabetes
Tanday, N., Zhu, W., Tarasov, A. I., Flatt, P. R. & Irwin, N., 27 Aug 2024, (Published online) In: Diabetes, Obesity and Metabolism. p. 1-13 13 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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Novel enzyme‐resistant pancreatic polypeptide analogs evoke pancreatic beta‐cell rest, enhance islet cell turnover, and inhibit food intake in mice
Zhu, W., Tanday, N., Lafferty, R. A., Flatt, P. R. & Irwin, N., 18 Apr 2024, (Published online) In: BioFactors.
Research output: Contribution to journal › Article › peer-review

Open Access
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1 Citation (Scopus)

19 Downloads (Pure)
2023
A novel peptide isolated from Aphonopelma chalcodes tarantula venom with benefits on pancreatic islet function and appetite control
Coulter-Parkhill, A., Dobbin, S., Tanday, N., Gault, V. A., McClean, S. & Irwin, N., 30 Jun 2023, In: Biochemical Pharmacology. 212, p. 1-9 10 p., 115544.
Research output: Contribution to journal › Article › peer-review

Open Access
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2 Citations (Scopus)

69 Downloads (Pure)
Sex-based impact of pancreatic islet stressors in GluCreERT2/Rosa26-eYFP mice
Tanday, N., Coulter-Parkhill, A., Moffett, R. C., Suruli, K., Dubey, V., Flatt, P. R. & Irwin, N., 25 Sept 2023, (Published online) In: Journal of Endrocrinology. 259, 2, p. 1-13 13 p., e230174.
Research output: Contribution to journal › Article › peer-review

Open Access
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1 Citation (Scopus)

17 Downloads (Pure)
Sustained metabolic benefits of ΔTRTX‐Ac1, a tarantula venom‐derived peptide, when administered together with exenatide in high‐fat fed mice
Coulter‐Parkhill, A., Tanday, N., Cobice, D., McLaughlin, C. M., McClean, S., Gault, V. A. & Irwin, N., 11 Oct 2023, (Published online) In: Diabetes, Obesity and Metabolism. 26, 1, p. 329-338 10 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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2 Citations (Scopus)

18 Downloads (Pure)
The glucagon receptor antagonist desHis1Pro4Glu9-glucagon(Lys12PAL) alters alpha-cell turnover and lineage in mice, but does not cause alpha-cell hyperplasia
Lafferty, R., Tanday, N., Dubey, V., Coulter-Parkhill, A., Vishal, K., Moffett, R. C., O'Harte, F., Flatt, P. R. & Irwin, N., 18 Apr 2023, In: Molecular and Cellular Endocrinology. 570, p. 1-8 9 p., 111932.
Research output: Contribution to journal › Article › peer-review

Open Access
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2 Citations (Scopus)

73 Downloads (Pure)
2022
Beneficial metabolic effects of recurrent periods of beta‐cell rest and stimulation using stable neuropeptide Y1 and glucagon‐like peptide‐1 receptor agonists
Tanday, N., Lafferty, R. A., Flatt, P. R. & Irwin, N., Dec 2022, In: Diabetes, Obesity and Metabolism. 24, 12, p. 2353-2363 11 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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10 Citations (Scopus)

78 Downloads (Pure)
2021
Beneficial impact of Ac3IV, an AVP analogue acting specifically at V1a and V1b receptors, on diabetes islet morphology and transdifferentiation of alpha- and beta-cells
Mohan, S., Lafferty, R., Tanday, N., Flatt, P., Moffett, C. & Irwin, N., Dec 2021, In: PLoS ONE. 16, 12, p. e0261608 e0261608.
Research output: Contribution to journal › Article › peer-review

Open Access
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6 Citations (Scopus)

47 Downloads (Pure)
Benefits of Sustained Upregulated Unimolecular GLP-1 and CCK Receptor Signalling in Obesity-Diabetes
Tanday, N., English, A., Lafferty, R., Flatt, P. & Irwin, N., 14 May 2021, In: Frontiers in Endocrinology. 12, p. 674704 13 p., 674704.
Research output: Contribution to journal › Article › peer-review

Open Access
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12 Citations (Scopus)

59 Downloads (Pure)
Enzymatically stable analogue of the gut-derived peptide xenin on beta-cell transdifferentiation in high fat fed and insulin-deficient Ins1Cre/+;Rosa26-eYFP mice
Tanday, N., Moffett, C., Gault, V. A., Flatt, P. & Irwin, N., 31 Mar 2021, In: Diabetes/Metabolism Research and Reviews. 37, 3, p. 1-10 10 p., e3384.
Research output: Contribution to journal › Article › peer-review

Open Access
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10 Citations (Scopus)

36 Downloads (Pure)
Positive Effects of NPY1 Receptor Activation on Islet Structure Are Driven by Pancreatic Alpha- and Beta-Cell Transdifferentiation in Diabetic Mice
Lafferty, R., Tanday, N., Moffett, C., Reimann, F., Gribble, F., Flatt, P. & Irwin, N., 25 Feb 2021, In: Frontiers in Endocrinology. 12, p. 633625 10 p., 633625.
Research output: Contribution to journal › Article › peer-review

Open Access
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20 Citations (Scopus)

81 Downloads (Pure)
2020
Antidiabetic drug therapy alleviates type 1 diabetes in mice by promoting pancreatic α-cell transdifferentiation
Sarnobat, D. S., Moffett, C., Tanday, N., Reimann, F., Gribble, F., Flatt, P. & Tarasov, A., 31 Dec 2020, In: Biochemical Pharmacology. 182, p. 1-10 10 p., 114216.
Research output: Contribution to journal › Article › peer-review

Open Access
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18 Citations (Scopus)

9 Downloads (Pure)
Beneficial actions of a long-acting apelin analogue in diabetes are related to positive effects on islet cell turnover and transdifferentiation
Tanday, N., Irwin, N., Moffett, C., Flatt, P. & O'Harte, F., 31 Dec 2020, In: Diabetes, Obesity and Metabolism. 22, 12, p. 2468-2478 11 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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22 Citations (Scopus)

31 Downloads (Pure)
Dapagliflozin exerts positive effects on beta cells, decreases glucagon and does not alter beta- to alpha-cell transdifferentiation in mouse models of diabetes and insulin resistance
Tanday, N., Irwin, N., Flatt, P. & Moffett, C., 31 Jul 2020, In: Biochemical Pharmacology. 177, 9 p., 114009.
Research output: Contribution to journal › Article › peer-review

Open Access
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23 Citations (Scopus)

70 Downloads (Pure)
Development and characterisation of a peptidergic N- and C-terminally stabilised mammalian NPY1R agonist which protects against diabetes induction
Lafferty, R., Tanday, N., Flatt, P. & Irwin, N., 31 May 2020, In: BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS. 1864, 5, 129543.
Research output: Contribution to journal › Article › peer-review

Open Access
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12 Citations (Scopus)

127 Downloads (Pure)
Generation and characterisation of C-terminally stabilised PYY molecules with potential in vivo NPYR2 activity
Lafferty, R., Tanday, N., Flatt, P. & Irwin, N., 1 Oct 2020, In: Metabolism. 111, 154339.
Research output: Contribution to journal › Article › peer-review

Open Access
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9 Citations (Scopus)

13 Downloads (Pure)
Liraglutide and sitagliptin counter beta- to alpha-cell transdifferentiation in diabetes
Tanday, N., Flatt, P., Irwin, N. & Moffett, C., 1 Apr 2020, In: Journal of Endrocrinology. 245, 1, p. 53-64 12 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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36 Citations (Scopus)

132 Downloads (Pure)
Peptide YY (1–36) peptides from phylogenetically ancient fish targeting mammalian neuropeptide Y1 receptors demonstrate potent effects on pancreatic β-cell function, growth and survival
Lafferty, R., Tanday, N., Mc Closkey, A., Bompada, P., De Marinis, Y., Flatt, P. & Irwin, N., 31 Mar 2020, In: Diabetes, Obesity and Metabolism. 22, 3, p. 404-416 13 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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21 Citations (Scopus)

254 Downloads (Pure)
2019
Effects of long-acting GIP, xenin and oxyntomodulin peptide analogues on alpha-cell transdifferentiation in insulin-deficient diabetic GluCreERT2;ROSA26-eYFP mice
Sarnobat, D. S., Moffett, C., Gault, V. A., Tanday, N., Reimann, F., Gribble, F., Flatt, P. & Irwin, N., 16 Nov 2019, (Published online) In: Peptides. 125, 9 p., 170205.
Research output: Contribution to journal › Article › peer-review

Open Access
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23 Citations (Scopus)

25 Downloads (Pure)
2018
Exendin-4(Lys27PAL)/gastrin/xenin-8-Gln: a novel acylated GLP-1/gastrin/xenin hybrid peptide that improves metabolic status in obese-diabetic (ob/ob) mice
Hasib, A., NG, T., Tanday, N., Craig, S., Gault, V. A., Flatt, P. & Irwin, N., 30 Nov 2018, In: Diabetes/Metabolism Research and Reviews. 35, 3, p. e3106
Research output: Contribution to journal › Article › peer-review

Open Access
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15 Citations (Scopus)

51 Downloads (Pure)