• Cromore Road, Coleraine Campus

    BT52 1SA Coleraine

    United Kingdom

  • 1084 Citations
  • 15 h-Index
20092020

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Article
2020

Albumin Nano-Encapsulation of Piceatannol Enhances Its Anticancer Potential in Colon Cancer Via Downregulation of Nuclear p65 and HIF-1 alpha

A.a. Aljabali, Bakshi, H., L. Hakkim, A. Haggag, M. Al-batanyeh, S. Al Zoubi, Al-trad, B., Nasef, M., Satija, S., Mehta, P., Pabreja, K., Mishra, V., Khan, M., Abobaker, Azzouz, Dureja, H., Pabari, Dardouri, Kesharwani, P., Gupta, S. & 11 others, Dhar Shukla, Prasher, B. Charbe, Negi, S., N. Kapoor, Chellappan, D. K., Webba da Silva, M., Thompson, J., Dua, H. S., McCarron, P. & Tambuwala, M., 1 Jan 2020, In : Cancers. 12, 1, p. 113

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
1 Downloads (Pure)

Anti-bacterial activity of inorganic nanomaterials and their antimicrobial peptide conjugates against resistant and non-resistant pathogens

Pardhi, D. M., Şen Karaman, D., Timonen, J., Wu, W., Zhang, Q., Satija, S., Mehta, M., Charbe, N., Mccarron, P., Tambuwala, M., Bakshi, H. A., Negi, P., Aljabali, A. A., Dua, K., Chaellappan, D. K., Behera, A., Pathak, K., Watharkar, R. B., Rautio, J. & Rosenholm, J. M., 12 Jun 2020, In : International Journal of Pharmaceutics. 586, 21 p., 119531.

Research output: Contribution to journalArticle

Circadian rhythm disruption and Alzheimer’s disease: The dynamics of a vicious cycle

Sharma, A., Sethi, G., Tambuwala, M. M., Aljabali, A. A. A., Chellappan, D. K., Dua, K. & Goyal, R., 28 Apr 2020, In : Current Neuropharmacology. 18, 35 p.

Research output: Contribution to journalArticle

COVID-19 pandemic: an overview of epidemiology, pathogenesis, diagnostics and potential vaccines and therapeutics

Amawi, H., Abu Deiab, G. I., A Aljabali, A. A., Dua, K. & Tambuwala, M. M., 12 May 2020, In : Therapeutic Delivery. 11, 4, p. 245-268 24 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Current Biological and Pharmacological updates on Wogonin

Rawat, S., Gupta, G., Pathak, S., Singh, S. K., Singh, H., Mishra, A., Gilhotra, R., Aljabali, A. A. A., Dureja, H., Tambuwala, M. M., Chellappan, D. K. & Dua, K., 13 May 2020, In : EXCLI. 19, p. 635-640 5 p.

Research output: Contribution to journalArticle

Open Access
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8 Downloads (Pure)

Development of a novel HPTLC fingerprint method for simultaneous estimation of berberine and rutin in medicinal plants and their pharmaceutical preparations followed by its application in antioxidant assay

Satija, S., Tambuwala, M. M., Pabreja, K., Bakshi, H. A., Chellappan, D. K., Aljabali, A. A., Nammi, S., Singh, T. G., Dureja, H., Gupta, G., Dua, K., Mehta, M. & Garg, M., 28 Jul 2020, In : JPC – Journal of Planar Chromatography – Modern TLC. 13 p.

Research output: Contribution to journalArticle

Dietary Crocin is Protective in Pancreatic Cancer while Reducing Radiation-Induced Hepatic Oxidative Damage

Bakshi, H. A., Zoubi, M. S. A., Faruck, H. L., Aljabali, A. A. A., Rabi, F. A., Hafiz, A. A., Al-batanyeh, K. M., Al-trad, B., Ansari, P., Nasef, M. M., Charbe, N. B., Satija, S., Mehta, M., Mishra, V., Gupta, G., Abobaker, S., Negi, P., Azzouz, I. M., Dardouri, A. A. K., Dureja, H. & 7 others, Prasher, P., Chellappan, D. K., Dua, K., Silva, M. W. D., Tanani, M. E., Mccarron, P. A. & M. Tambuwala, M., 26 Jun 2020, In : Nutrients. 12, 6, p. 1901 18 p.

Research output: Contribution to journalArticle

Open Access
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Efficacy of resveratrol encapsulated microsponges delivered by pectin based matrix tablets in rats with acetic acid-induced ulcerative colitis

Gandhi, H., Rathore, C., Dua, K., Vihal, S., Tambuwala, M. M. & Negi, P., 3 Mar 2020, In : Drug Development and Industrial Pharmacy. 46, 3, p. 365-375 11 p.

Research output: Contribution to journalArticle

Emerging era of “somes”: polymersomes as versatile drug delivery carrier for cancer diagnostics and therapy

Sharma, A. K., Prasher, P., Aljabali, A. A., Mishra, V., Gandhi, H., Kumar, S., Mutalik, S., Chellappan, D. K., Tambuwala, M. M., Dua, K. & Kapoor, D. N., 5 Jun 2020, In : Drug Delivery and Translational Research. 20 p.

Research output: Contribution to journalArticle

Emerging therapeutic potential of the iridoid molecule, asperuloside: A snapshot of its underlying molecular mechanisms

Chan, Y., Ng, S. W., Xin Tan, J. Z., Gupta, G., Tambuwala, M. M., Bakshi, H. A., Dureja, H., Dua, K., Ishaq, M., Caruso, V. & Chellappan, D. K., 5 Jan 2020, In : Chemico-Biological Interactions. 315, 43 p., 108911.

Research output: Contribution to journalArticle

Emerging trends in clinical implications of bio-conjugated silver nanoparticles in drug delivery

Prasher, P., Sharma, M., Mudila, H., Gupta, G., Sharma, A. K., Kumar, D., Bakshi, H. A., Negi, P., Kapoor, D. N., Chellappan, D. K., Tambuwala, M. M. & Dua, K., 1 Mar 2020, In : Colloid and Interface Science Communications. 35, 13 p., 100244.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Enhanced oral bioavailability and hepatoprotective activity of thymoquinone in the form of phospholipidic nano-constructs

Rathore, C., Upadhyay, N., Kaundal, R., Dwivedi, R. P., Rahatekar, S., John, A., Dua, K., Tambuwala, M., Jain, S., Chaudari, D. & Negi, P., 1 Feb 2020, In : Expert Opinion on Drug Delivery. 17, 2, p. 237-253 17 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Going beyond antibiotics: Natural plant extracts as an emergent strategy to combat biofilm-associated infections

Kou, J., Xin, T. Y., Mccarron, P., Gupta, G., Dureja, H., Satija, S., Mehta, M., Bakshi, H. A., Tambuwala, M. M., Collet, T., Dua, K. & Chellappan, D. K., 25 Apr 2020, In : Journal of Environmental Pathology, Toxicology and Oncology. 39, 2, p. 125-136 12 p.

Research output: Contribution to journalArticle

Immunological axis of berberine in managing inflammation underlying chronic respiratory inflammatory diseases

Tew, X. N., Xin Lau, N. J., Chellappan, D. K., Madheswaran, T., Zeeshan, F., Tambuwala, M. M., Aljabali, A. A., Balusamy, S. R., Perumalsamy, H., Gupta, G., Oliver, B. G., Hus, A., Wark, P., Reddy, K., Wadhwa, R., Hansbro, P. M. & Dua, K., 1 Feb 2020, In : Chemico-Biological Interactions. 317, 46 p., 108947.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Molecular mechanisms of action of naringenin in chronic airway diseases

Chin, L. H., Hon, C. M., Chellappan, D. K., Chellian, J., Madheswaran, T., Zeeshan, F., Awasthi, R., Aljabali, A. A., Tambuwala, M. M., Dureja, H., Negi, P., Kapoor, D. N., Goyal, R., Paudel, K. R., Satija, S., Gupta, G., Hsu, A., Wark, P., Mehta, M., Wadhwa, R. & 2 others, Hansbro, P. M. & Dua, K., 15 Jul 2020, In : European Journal of Pharmacology. 879, 37 p., 173139.

Research output: Contribution to journalArticle

Monotherapy of RAAS blockers and mobilization of aldosterone: A mechanistic perspective study in kidney disease

Gupta, G., Dahiya, R., Singh, Y., Mishra, A., Verma, A., Gothwal, S. K., Aljabali, A. A. A., Dureja, H., Prasher, P., Negi, P., Kapoor, D. N., Goyal, R., Tambuwala, M. M., Chellappan, D. K. & Dua, K., 4 Feb 2020, In : Chemico-Biological Interactions. 317, 108975.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Nanocarriers: more than tour de force for thymoquinone

Rathore, C., Rathbone, M. J., Chellappan, D. K., Tambuwala, M. M., Pinto, T. D. J. A., Dureja, H., Hemrajani, C., Gupta, G., Dua, K. & Negi, P., 2 Apr 2020, In : Expert Opinion on Drug Delivery. 17, 4, p. 479-494 16 p.

Research output: Contribution to journalArticle

Open Access
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5 Downloads (Pure)

Plants derived therapeutic strategies targeting chronic respiratory diseases: Chemical and immunological perspective

Prasher, P., Sharma, M., Mehta, M., Paudel, K. R., Satija, S., Chellappan, D. K., Dureja, H., Gupta, G., Tambuwala, M. M., Negi, P., Wich, P. R., Hansbro, N., Hansbro, P. M. & Dua, K., 1 Jul 2020, In : Chemico-Biological Interactions. 325, 62 p., 109125.

Research output: Contribution to journalArticle

Probing 3CL protease: Rationally designed chemical moieties for COVID ‐19

Sharma, M., Prasher, P., Mehta, M., Zacconi, F. C., Singh, Y., Kapoor, D. N., Dureja, H., Pardhi, D. M., Tambuwala, M. M., Gupta, G., Chellappan, D. K., Dua, K. & Satija, S., 30 Jul 2020, In : Drug Development Research. 8 p.

Research output: Contribution to journalArticle

Role of immune checkpoint inhibitors in the revolutionization of advanced melanoma care

Singh, S., Numan, A., Agrawal, N., Tambuwala, M. M., Singh, V. & Kesharwani, P., 30 Jun 2020, In : International Immunopharmacology. 83, 7 p., 106417.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Role of Serine/Threonine Kinase 11 (STK11) or liver kinase B1 (LKB1) Gene in Peutz-Jeghers Syndrome

Altamish, M., Dahiya, R., Singh, A. K., Mishra, A., Aljabali, A. A. A., Satija, S., Mehta, M., Dureja, H., Prasher, P., Negi, P., Kapoor, D. N., Goyal, R., Tambuwala, M. M., Chellappan, D. K., Dua, K. & Gupta, G., 12 May 2020, In : Critical Reviews in Eukaryotic Gene Expression. 19 p.

Research output: Contribution to journalArticle

The Secondary Bile acids, Ursodeoxycholic acid and Lithocholic Acid, Protect Against Intestinal Inflammation by Inhibition of Epithelial Apoptosis

Lajczak-McGinley, N. K., Porru, E., Fallon, C. M., Smyth, J., Curley, C., McCarron, P. A., Tambuwala, M. M., Roda, A. & Keely, S. J., 19 Jun 2020, In : Physiological Reports. 8, 12, 11 p., e14456.

Research output: Contribution to journalArticle

Open Access
File
2019
10 Citations (Scopus)
18 Downloads (Pure)

Central Composite Designed Formulation, Characterization and In-Vitro Cytotoxic effect of Erlotinib Loaded Chitosan Nanoparticulate System

Pandey, P., Chellappan, D. K., Tambuwala, M. M., Bakshi, H., Dua, K. & Dureja, H., 1 Dec 2019, In : International Journal of Biological Macromolecules. 141, p. 596-610 15 p.

Research output: Contribution to journalArticle

Open Access

Dynamics of Prolyl hydroxylases levels during disease progression in experimental colitis

Bakshi, H. A., Mishra, V., Satija, S., Mehta, M., Hakkim, F. L., Kesharwani, P., Dua, K., Chellappan, D. K., Charbe, N. B., Shrivastava, G., Rajeshkumar, S., Aljabali, A. A., Al-trad, B., Pabreja, K. & Tambuwala, M. M., 1 Dec 2019, In : Inflammation. 42, 6, p. 2032-2036 5 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
4 Downloads (Pure)

FRANKINCENSE ESSENTIAL OIL SUPPRESSES MELANOMA CANCER THROUGH DOWN REGULATION OF BCL-2/BAX CASCADE SIGNALING AND AMELORATE HEPTOTOXICITY VIA PHASE I AND II DRUG METABOLISING ENZYMES

Faruk, H., Bakshi, H., Khan, S., Nasef, M., Farzand, R., Rashan, L., MS, A-B., SS, H., McCarron, P. A. & Tambuwala, M. M., 28 May 2019, In : Oncotarget. 10, 37, p. 3472 3490 p.

Research output: Contribution to journalArticle

Open Access
File
47 Downloads (Pure)

Gold-coated plant virus as computed tomography imaging contrast agent

Aljabali, A. A. A., Al Zoubi, M. S., Al-Batanyeh, K. M., Al-Radaideh, A., Obeid, M. A., Al Sharabi, A., Alshaer, W., AbuFares, B., Al-Zanatil, T., Tambuwala, M. M., Akbar, N. & Evans, D. J., 7 Oct 2019, In : Beilstein Journal of Nanotechnology. 10, p. 1983-1993 11 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
9 Downloads (Pure)
Open Access
File
1 Citation (Scopus)
18 Downloads (Pure)

Hypoxia-inducible factor (HIF) hydroxylase inhibition enhances the protective effects of cyclosporine in colitis.

Halligan, D., Khan, M., Brown, E., Rowan, C., Coulter, I. S., Doherty, G., Tambuwala, M. M. & Taylor, C. T., 29 Apr 2019, (Accepted/In press) In : AJP - Gastrointestinal and Liver Physiology.

Research output: Contribution to journalArticle

File
4 Downloads (Pure)

In Vivo Anti Cancer Potential of Pyrogallol in Murine Model of Colon Cancer

Bakshi, H. & Tambuwala, M. M., 2 Sep 2019, In : Asian Pac J Cancer Prev. 20, 9, p. 2645-2651 7 p.

Research output: Contribution to journalArticle

Open Access
File
22 Downloads (Pure)

Molecular signaling of G‐protein‐coupled receptor in chronic heart failure and associated complications

Altamish, M., Samuel, V. P., Dahiya, R., Singh, Y., Deb, P. K., Bakshi, H. A., Tambuwala, M. M., Chellappan, D. K., Collet, T., Dua, K. & Gupta, G., 30 Nov 2019, In : Drug Development Research. 9 p.

Research output: Contribution to journalArticle

Preparation, characterization and in-vitro efficacy of quercetin loaded liquid crystalline nanoparticles for the treatment of asthma

Cherk Yong, D. O., Saker, S. R., Wadhwa, R., Chellappan, D. K., Madheswaran, T., Panneerselvam, J., Tambuwala, M. M., Bakshi, H. A., Kumar, P., Pillay, V., Gupta, G., Oliver, B. G., Wark, P., Hsu, A., Hansbro, P. M., Dua, K. & Zeeshan, F., 31 Dec 2019, In : Journal of Drug Delivery Science and Technology. 54, 8 p., 101297.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Smart dendrimers: Synergizing the targeting of anticancer bioactives

Saluja, V., Mankoo, A., Saraogi, G., Tambuwala, M. M. & Mishra, V., 1 Aug 2019, In : Journal of Drug Delivery Science and Technology. 52, p. 15-26 12 p., 52.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
13 Downloads (Pure)
Open Access
File
5 Downloads (Pure)
Open Access
File
8 Citations (Scopus)
3 Downloads (Pure)

Nanoneuromedicine for management of neurodegenerative disorder

Dwivedi, N., Shah, J., Mishra, V., Tambuwala, M. M. & Kesharwani, P., 21 Dec 2018, In : Journal of Drug Delivery Science and Technology. 49, p. 477-490 13 p.

Research output: Contribution to journalArticle

Open Access
File
14 Citations (Scopus)
35 Downloads (Pure)
2017

Application of three-dimensional printing for colon targeted drug delivery systems

Charbe, N. B., McCarron, P. A., Lane, M. E. & Tambuwala, M. M., 8 Aug 2017, In : International Journal of Pharmaceutical Investigation. 7, 2, p. 47-59

Research output: Contribution to journalArticle

Open Access
Open Access
File
16 Citations (Scopus)
14 Downloads (Pure)
Open Access
File
7 Citations (Scopus)
21 Downloads (Pure)

Intermittent hypoxia in obstructive sleep apnoea mediates insulin resistance through adipose tissue inflammation

Murphy, A., Thomas, A., Crinion, S., Kent, B., Tambuwala, M., Fabre, A., PEPIN, J-L., Roche, H., ARNAUD, C. & Ryan, S., 19 Apr 2017, In : European Respiratory Journal. 49, p. 1-11 11 p.

Research output: Contribution to journalArticle

Open Access
40 Citations (Scopus)
20 Citations (Scopus)
11 Downloads (Pure)

Three-dimensional (3D) bio-printing: A new frontier in oncology research

Charbe, N., McCarron, P. & Tambuwala, M., 10 Feb 2017, In : World Journal of Clinical Oncology. 8, 1, p. 21-36

Research output: Contribution to journalArticle

Open Access
File
24 Citations (Scopus)
23 Downloads (Pure)

Ursodeoxycholic acid and lithocholic acid exert anti-inflammatory actions in the colon

Ward, J. B. J., Lajczak, N. K., Kelly, O. B., O'Dwyer, A. M., Giddam, A. K., Ní Gabhainn, J. N., Franco, P., Tambuwala, M. M., Jefferies, C. A., Keely, S., Roda, A. & Keely, S. J., 30 Mar 2017, In : AJP - Gastrointestinal and Liver Physiology. 312, 6, p. G550-G558

Research output: Contribution to journalArticle

Open Access
File
40 Citations (Scopus)
55 Downloads (Pure)
2016

Hydroxylases regulate intestinal fibrosis through the suppression of ERK mediated TGF-β1 signaling

Cabrero Manresa, M., Tambuwala, M. M., Radhakrishnan, P., Harnoss, J. M., Brown, E., Cavadas, M. A., Keogh, C. E., Cheong, A., Barrett, K. E., Cummins, E. P., Schneider, M. & Taylor, C. T., 1 Dec 2016, In : AJP - Gastrointestinal and Liver Physiology. 311, 6, p. G1076-G1090

Research output: Contribution to journalArticle

Open Access
File
11 Citations (Scopus)
93 Downloads (Pure)

Prolyl hydroxylase-1 regulates hepatocyte apoptosis in an NF-kB-dependent manner

Fitzpatrick, S. F., Fábián, Z., Schaible, B., Lenihan, C. R., Schwarzl, T., Rodriguez, J., Zheng, X., Li, Z., Tambuwala, M. M., Higgins, D. G., O'Meara, Y., Slattery, C., Manresa, M. C., Fraisl, P., Bruning, U., Baes, M., Carmeliet, P., Doherty, G. & Kriegsheim, A. V., 27 Apr 2016, In : Biochemical and Biophysical Research Communications. 474, 3, p. 579-586

Research output: Contribution to journalArticle

Open Access
File
15 Citations (Scopus)
25 Downloads (Pure)

REST is a hypoxia-responsive transcriptional repressor

Cavadas, M. A. S., Mesnieres, M., Crifo, B., Manresa, M. C., Selfridge, A. C., Keogh, C. E., Fabian, Z., Scholz, C. C., Nolan, K. A., Rocha, L. M. A., Tambuwala, M., Brown, S., Wdowicz, A., Corbett, D., Murphy, K. J., Godson, C., Cummins, E. P., Taylor, C. T. & Cheong, A., 17 Aug 2016, In : Scientific Reports. 6, 31355, p. 1-22

Research output: Contribution to journalArticle

Open Access
File
21 Citations (Scopus)
11 Downloads (Pure)
2015

Chronic Intermittent Hypoxia Contributes To Pro-Inflammatory Macrophage Alteration In Visceral Adipose Tissue Of Lean And Obese Mice

Murphy, A. M., Thomas, A., Tambuwala, M., McNicholas, W. T., Roche, H. M., Taylor, C. T., Pepin, J-L., Arnaud, C. & Ryan, S., 18 May 2015, In : American Journal of Respiratory and Critical Care Medicine. B30, p. 2691-2691

Research output: Contribution to journalArticle

Open Access
12 Citations (Scopus)