Dr. Ming-Wei Chang jointed the School of Engineering (University of Ulster) in 2019 to explore novel strategies of designing and manufacturing advanced devices for application in key areas such as healthcare. Prior to this he served as an Associate Professor of Biomedical Engineering at Zhejiang University. He was nominated as a member of the FIT academic committee of Zhejiang University and as a member of the Oversea’s High-level Talents of Zhejiang Province, China. He was awarded his PhD in Biomedical Engineering from University College London (2011) and continued his research as a postdoctoral researcher in the Institute of Biomedical Engineering at the University of Oxford. From 2003-2008, he served as an R&D manager and principal investigator at the Industrial Technology Research Institute (ITRI, Taiwan).

So far, he has supervised numerous PhD students (including national and international) in addition to undergraduates, MSC students and postdoc researchers. He has published over 70 scientific articles and has been granted 35 international patents (including IPO: US, UK, Taiwan, Japan, and China) in the development of sensors, natural products and healthcare devices for biomedical applications. Currently, he is working on smart new materials and methodologies to engineer novel micro/nanostructures for biomedical applications and healthcare technologies. He has served as a guest editor, keynote speaker and has peer reviewed for all major academic publishers including RSC, ACS, Elsevier, and Wiley.

Selected papers:

1.     High Precision 3D Printing:

- 3D electrohydrodynamic printing of highly aligned dual-core graphene composite matrices, B Wang, X Chen, Z Ahmad, J Huang, MW Chang*, Carbon 153, 285-297, 2019. https://www.sciencedirect.com/science/article/pii/S0008622319307171

- Precision Printing of Customized Cylindrical Capsules with Multifunctional Layers for Oral Drug Delivery, X.Li, C. Zhang, S. Wu, Xing Chen, John Mai, Ming-Wei Chang*, ACS applied materials & interfaces, 2019. https://pubs.acs.org/doi/abs/10.1021/acsami.9b13568

- Development of random and ordered composite fiber hybrid technologies for controlled release functions, B Wang, Z Ahmad, J Huang, JS Li, MW Chang*, Chemical Engineering Journal, 343, 379-389, 2018. https://www.sciencedirect.com/science/article/pii/S1385894718303620

- Three-dimensional electrohydrodynamic printing and spinning of flexible composite structures for oral multidrug forms, S Wu, JS Li, J Mai, MW Chang*, ACS applied materials & interfaces 10 (29), 24876-24885, 2018.https://pubs.acs.org/doi/10.1021/acsami.8b08880

 2.     Multifunctional Particles:

- Porous Yolk–Shell Particle Engineering via Nonsolvent-Assisted Trineedle Coaxial Electrospraying for Burn-Related Wound Healing, C Zhang, Y Li, Y Hu, Y Peng, Z Ahmad, JS Li, MW Chang*, ACS applied materials & interfaces 11 (8), 7823-7835. https://pubs.acs.org/doi/10.1021/acsami.8b22112

- Tri-needle coaxial electrospray engineering of magnetic polymer yolk–shell particles possessing dual-imaging modality, multiagent compartments, and trigger release potential, C Zhang, ZC Yao, Q Ding, JJ Choi, Z Ahmad, MW Chang*, JS Li, ACS applied materials & interfaces 9 (25), 21485-21495, 2017. https://pubs.acs.org/doi/10.1021/acsami.7b05580

- Targeting oxidative stress using tri-needle electrospray engineered Ganoderma lucidum polysaccharide-loaded porous yolk-shell particles, Z Xing, C Zhang, C Zhao, Z Ahmad, JS Li, MW Chang* European Journal of Pharmaceutical Sciences 125, 64-73, 2018. https://www.sciencedirect.com/science/article/pii/S0928098718304378

 3.     Centrifugal fiber generation:

- High throughput engineering and use of multi-fiber composite matrices for controlled active release, L Wang, C Zhang, HMD Wang, Z Ahmad, JS Li, MW Chang*, Materials Today Communications 17, 53-59, 2018.

- Multi-compartment centrifugal electrospinning based composite fibers, L Wang, Z Ahmad, J Huang, JS Li, MW Chang*, Chemical Engineering Journal 330, 541-549, 2017.

- Mass and controlled fabrication of aligned PVP fibers for matrix type antibiotic drug delivery systems, L Wang, MW Chang, Z Ahmad, H Zheng, JS Li, Chemical Engineering Journal 307, 661-669, 2017.

 4.     Electrospun micro/nano fibers:

- A novel core-shell nanofiber drug delivery system intended for the synergistic treatment of melanoma, LF Zhu, Y Zheng, J Fan, Y Yao, Z Ahmad, MW Chang*, European Journal of Pharmaceutical Sciences 137, 105002, 2019.

- Nanoporous hollow fibers as a phantom material for the validation of diffusion magnetic resonance imaging, C Zhang, Q Ding, H He, Y Peng, C Li, J Mai, JS Li, J Zhong, MW Chang*, Journal of Applied Polymer Science 136 (23), 47617, 2019.

- Designer fibers from 2D to 3D–Simultaneous and controlled engineering of morphology, shape and size, ZC Yao, C Zhang, Z Ahmad, J Huang, JS Li, MW Chang*, Chemical Engineering Journal 334, 89-98, 2018.

5.     New biomaterial synthesis:

- Ultrasound-assisted synthesis of chitosan from fungal precursors for biomedical applications, LF Zhu, JS Li, J Mai, MW Chang*, Chemical Engineering Journal 357, 498-507, 2019.

- Development of Ganoderma lucidum spore powder based proteoglycan and its application in hyperglycemic, antitumor and antioxidant function, LF Zhu, Y Yao, Z Ahmad, MW Chang*, Process Biochemistry, 2019.

- Synthesis and Evaluation of Herbal Chitosan from Ganoderma Lucidum Spore Powder for Biomedical Applications, LF Zhu, ZC Yao, Z Ahmad, JS Li, MW Chang*, Scientific Reports 8 (1), 14608, 2018.

Awards and Honors:

- Young Innovative Principal Investigator, ZJU, China, 2017.

- Outstanding Achievement Award, ZJU, China, 2017.

- Supervisory Excellence Award, ZJU, China, 2015.

- Best Poster Award, China-Europe Symposium on Biomaterials in Regenerative Medicine, 2015.

- Supervisory Excellence Award, ZJU, China, 2014.

- Qiushi Outstanding Young Scholar Award, China, 2013.

- Oversea High-level Talents of Zhejiang Province, China, 2013.

- OSA Association Scholarship Award, UCL, UK, 2010.

- Oversea Research Scholarship (ORS) Award, UK, 2009.

- OSA Association Scholarship Award, UCL, UK, 2009.

- Best Invention Awards, ITRI, Taiwan, 2007.

- ITRI Elite Award, ITRI, Taiwan, 2007.

- The Outstanding Research Silver-Award, ITRI, Taiwan, 2007.

- The Best Paper Award, ASME, US, 2007.

- The Phi Tau Phi Scholastic Honorary Member, 2002.

Selected Patents:

l Electrostatic spinning device for continuously preparing spiral micro-nanofibers and method of electrostatic spinning device, MW Chang, CC Zhang, JS Li, CN20171226A

l Method of fabricating capacitive ultrasonic transducers, MW Chang, TJ Gwo, TM Deng, ZY Chung, US Patent 7,937,834

l  Capacitive ultrasonic sensors and display devices using the same, MW Chang, D Hsu-Cheng, TJ Gwo, US Patent 7,856,883

l  Method of fabricating a polymer-based capacitive ultrasonic transducer, MW Chang, DC Pang, CS Tseng, US Patent 7,673,375

Keywords: High precision 3D printing, Nanotechnology, Drug delivery, Biomaterials, Sensors

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