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Michael Conlon

Prof

1991 …2020

Research output per year

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Research Output

2020
1 Citation (Scopus)

GIP renaissance

Flatt, PR. & Conlon, JM., 23 Jan 2020, (Accepted/In press) In : Peptides. 125, 170266.

Research output: Contribution to journalArticle

Isolation and characterization of cytotoxic and insulin-releasing components from the venom of the black-necked spitting cobra Naja nigricollis (Elapidae)

Conlon, JM., Attoub, S., Musale, V., Leprince, J., Casewell, N., Sanz, L. & Calvete, J., 30 Jun 2020, In : Toxicon. 6, 8 p., 100030.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
32 Downloads (Pure)
2019

Conformational analysis and in vitro immunomodulatory and insulinotropic properties of the frog skin host-defense peptide rhinophrynin-27 and selected analogs

Scorciapino, MA., Carta, P., Pantic, JM., Lukic, M. L., Lukic, A., Musale, V., Abdel-Wahab, Y. & Conlon, JM., 31 Dec 2019, In : Biochimie. 167, p. 198-206 9 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
9 Downloads (Pure)

Immunomodulatory, insulinotropic, and cytotoxic activities of phylloseptins and plasticin-TR from the Trinidanian leaf frog Phyllomedusa trinitatis.

Pantic, J., Guilhaudis, L., Musale, V., Attoub, S., Lukic, M. L., Mechkarska, M. & Conlon, JM., 31 Aug 2019, In : Journal of Peptide Science. e3153, 4, p. 1-10 10 p., e3153.

Research output: Contribution to journalArticle

Open Access
File

Insights into conformation and membrane interactions of the acyclic and dicarba‑bridged brevinin‑1BYa antimicrobial peptides

Timmons, PB., O'Flynn, D., Conlon, JM. & Hewage, C., 13 Aug 2019, (Accepted/In press) In : EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 48, 8, p. 701-710 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Peptidomic analysis in the discovery of therapeutically valuable peptides in amphibian skin secretions

Conlon, JM., Mechkarska, M. & Leprince, J., 11 Nov 2019, (Accepted/In press) In : Expert Review of Proteomics. 16, 11-12, p. 897-908

Research output: Contribution to journalArticle

1 Citation (Scopus)

Structural and positional studies of the antimicrobial peptide brevinin-1BYa in membrane-mimetic environments

Timmons, PB., O'Flynn, D., Conlon, JM. & Hewage, C., 12 Nov 2019, In : Journal of Peptide Science. 25, 11, e3208.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2018

Assessment of the potential of temporin peptides from the frog Rana temporaria (Ranidae) as anti‐diabetic agents

Musale, V., Casciaro, B., Mangoni, LM., Abdel-Wahab, YHA., Flatt, P. & Conlon, JM., 19 Jan 2018, In : Journal of Peptide Science. 24, p. e3065

Research output: Contribution to journalArticle

Open Access
7 Citations (Scopus)
Open Access
File
4 Citations (Scopus)
2 Downloads (Pure)

Identification of Components in Frog Skin Secretions with Therapeutic Potential as Antidiabetic Agents

Conlon, JM., Moffett, C., Leprince, J. & Flatt, P., 24 Feb 2018, In : Methods in Molecular Biology. 1719, p. 319-333

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)

Insulinotropic, glucose-lowering, and beta-cell anti-apoptotic actions of peptides related to esculentin-1a(1-21).NH2

Musale, V., Abdel-Wahab, YHA., Flatt, P., Conlon, J. M. & Mangoni, M. L., 7 Mar 2018, (Accepted/In press) In : Amino Acids. 50, 6, p. 723-724

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Insulinotropic activity of the host-defense peptide frenatin 2D: conformational, structure-function and mechanistic studies

Musale, V., Guilhaudis, L., Abdel-Wahab, Y., Flatt, PR. & Conlon, JM., 19 Sep 2018, In : Biochimie. 156, p. 12-21 9 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
4 Downloads (Pure)

Peptidomic analysis of the host-defense peptides in skin secretions of Rana graecaprovidesinsightintophylogeneticrelationshipsamongEurasianRana species

Mechkarska, M., Kolodziejek, J., Musale, V., Coquet, L., Leprince, J., Jouenne, T., Nowotny, N. & Conlon, JM., 27 Dec 2018, In : Comparative Biochemistry and Physiology - Part D: Genomics and Proteomics. 29, p. 228 234 p., Part D 29.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)

Peptidomic analysis of the host-defense peptides in skin secretions of the Trinidadian leaf frog Phyllomedusa trinitatis (Phyllomedusidae)

Mechkarska, M., Coquet, L., Leprince, J., Auguste, R., Jouenn, T. & Conlon, JM., 30 Jun 2018, In : Comparative Biochemistry and Physiology - Part D: Genomics and Proteomics. 28, p. 72-79

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
3 Downloads (Pure)

Towards establishing a higher acceptance rate for PEPTIDES - the peer review process and criteria for acceptance or rejection

Conlon, JM. & Herzig, K-H., 28 Nov 2018, In : Peptides. 112, p. 32 33 p.

Research output: Contribution to journalArticle

File
2 Citations (Scopus)
2017

Actions of PGLa-AM1 and its [A14K] and [A20K] analogues and their therapeutic potential as anti-diabetic agents

Owolabi, BO., Musalea, V., Ojo, OO., Moffett, C., McGahon, MK., Curtis, TM., Conlon, JM., Flatt, P. & Abdel-Wahab, YHA., 7 Apr 2017, In : Biochimie. 138, p. 1-12

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
28 Downloads (Pure)

Anti-diabetic actions of esculentin-2CHa(1–30) and its stable analogues in a diet-induced model of obesity-diabetes

Vasu, S., Ojo, O., Moffett, C., Conlon, JM., Flatt, P. & Abdel-Wahab, Y., 23 Aug 2017, In : Amino Acids. 49, 10, p. 1705-1717

Research output: Contribution to journalArticle

Open Access
7 Citations (Scopus)

Cytotoxic peptides with insulin-releasing activities from skin secretions of the Italian stream frog Rana italica (Ranidae)

Conlon, JM., Musale, V., Attoub, S., Mangoni, ML., Leprince, J., Coquet, L., Jouenne, T., Abdel-Wahab, YHA., Flatt, P. & Rinaldi, AC., 11 Jul 2017, In : Journal of Peptide Science. 23, 10, p. 769-776

Research output: Contribution to journalArticle

Open Access
9 Citations (Scopus)

Esculentin-2CHa(1–30) and its analogues: stability and mechanisms of insulinotropic action

Vasu, S., McGahon, M., Moffett, C., Curtis, T., Conlon, JM., Abdel-Wahab, YHA. & Flatt, P., 1 Mar 2017, In : Journal of Endrocrinology. 232, 3, p. 423-435 13 p.

Research output: Contribution to journalArticle

Open Access
File
12 Citations (Scopus)
19 Downloads (Pure)
Open Access
9 Citations (Scopus)

Peptides from frog skin with potential for development into agents for Type 2 diabetes therapy

Conlon, JM., Mechkarska, M., Abdel-Wahab, YHA. & Flatt, P., 2 Sep 2017, (Accepted/In press) In : Peptides. 100, p. 275-281

Research output: Contribution to journalArticle

Open Access
15 Citations (Scopus)
Open Access
4 Citations (Scopus)

The activity of the rectal gland of the North Pacific spiny dogfish Squalus suckleyi is glucose dependent and stimulated by glucagon-like peptide-1.

Deck, CA., Anderson, WG., Conlon, JM. & Walsh, PJ., 25 Apr 2017, In : Journal of Comparative Physiology B. 187, 8, p. 1155-1161

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
6 Downloads (Pure)

The Frog Skin Host-Defense Peptide Frenatin 2.1S Enhances Recruitment, Activation and Tumoricidal Capacity of NK Cells

Pantic, JM., Jovanovica, IP., Radosavljevica, GD., Gajovic, NM., Arsenijevic, NN., Conlon, JM. & Lukic, ML., 16 May 2017, In : Peptides. 93, p. 44-50

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

The Potential of Frog Skin-Derived Peptides for Development into Therapeutically-Valuable Immunomodulatory Agents

Pantic, JM., Jovanovic, IP., Radosavljevic, GD., Arsenijevic, NN., Conlon, JM. & Lukic, ML., 13 Dec 2017, In : Molecules. 22, 12, p. E2071-E2071

Research output: Contribution to journalArticle

Open Access
18 Citations (Scopus)
2016
Open Access
5 Citations (Scopus)
Open Access
File
17 Citations (Scopus)
11 Downloads (Pure)
Open Access
File
10 Citations (Scopus)
4 Downloads (Pure)

In vitro and in vivo insulinotropic properties of the multifunctional frog skin peptide hymenochirin-1B: a structure-activity study.

Owolabi, BO., Ojo, OO., Srinivasan, DK., Flatt, P., Conlon, JM. & Abdel-Wahab, Y., 1 Feb 2016, In : Amino Acids. 48, 2, p. 535-547

Research output: Contribution to journalArticle

Open Access
21 Citations (Scopus)

Molecular mechanisms mediating the beneficial metabolic effects of [Arg4]tigerinin-1R in mice with diet-induced obesity and insulin resistance

Ojo, OO., Srinivasan, DK., Owolabi, BO., McGahon, MK., Moffett, C., Curtis, TM., Conlon, JM., Flatt, P. & Abdel-Wahab, Y., 1 Aug 2016, In : Biological Chemistry. 397, 8, p. 753-764

Research output: Contribution to journalArticle

Open Access
14 Citations (Scopus)
Open Access
File
13 Citations (Scopus)
6 Downloads (Pure)

Peptidomic analysis of the extensive array of host-defense peptides in skin secretions of the dodecaploid frog Xenopus ruwenzoriensis (Pipidae)

Coqueta, L., Kolodziejek, J., Jouenne, T., Nowotny, N., King, JD. & Conlon, JM., 25 Aug 2016, In : Comparative Biochemistry and Physiology - Part D: Genomics and Proteomics. 19C, p. 18-24

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
17 Downloads (Pure)

Purification, Conformational Analysis, and Properties of a Family ofTigerinin Peptides from Skin Secretions of the Crowned BullfrogHoplobatrachus occipitalis

McLaughlin, CM., Lampis, S., Mechkarska, M., Coquet, L., Jouenne, T., King, JD., Mangoni, ML., Lukic, ML., Scorciapino, MA. & Conlon, J. M., 25 Aug 2016, In : Journal of Natural Products. N/A, p. 1-7

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
10 Downloads (Pure)
2015

Conformational Analysis of the Host-Defense Peptides Pseudhymenochirin-1Pb and -2Pa and Design of Analogues with Insulin-Releasing Activities and Reduced Toxicities

Manzo, G., Scorciapino, MA., Srinivasan, D., Attoub, S., Mangoni, ML., Flatt, P. & Conlon, JM., 24 Dec 2015, In : Journal of Natural Products. 78, 12, p. 3041-3048

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)

Esculentin-2CHa-Related Peptides Modulate Islet Cell Function and Improve Glucose Tolerance in Mice with Diet-Induced Obesity and Insulin Resistance.

Ojo, O., Srinivasan, DK., Owolabi, BO., Vasu, S., Conlon, J. M., Flatt, P. & Abdel-Wahab, Y., 29 Oct 2015, In : PLoS ONE. 10, 10, p. e0141549-e0141549

Research output: Contribution to journalArticle

Open Access
11 Citations (Scopus)
Open Access
9 Citations (Scopus)
2014

A family of antimicrobial and immunomodulatory peptides related to the frenatins from skin secretions of the Orinoco lime frog Sphaenorhynchus lacteus (Hylidae)

Conlon, J. M., Mechkarska, M., Radosavljevic, G., Attoub, S., King, J. D., Lukic, M. L. & McClean, S., 2014, In : Peptides. 56, 0, p. 132 - 140

Research output: Contribution to journalArticle

Open Access
17 Citations (Scopus)

Insulin-releasing and cytotoxic properties of the frog skin peptide, tigerinin-1R: a structure-activity study

Srinivasan, D., Ojo, O., Abdel-Wahab, Y., Flatt, P., Guilhaudis, L. & Conlon, JM., 12 Feb 2014, In : Peptides. 55, p. 23-31

Research output: Contribution to journalArticle

20 Citations (Scopus)

Magainin-AM2 improves glucose homeostasis and beta cell function in high-fat fed mice.

Ojo, O., Srinivasan, DK., Owolabi, BO., Conlon, JM., Flatt, P. & Abdel-Wahab, Y., 20 Oct 2014, In : Biochim Biophys Acta. 1850, 1, p. 80-87

Research output: Contribution to journalArticle

Open Access
14 Citations (Scopus)
101 Citations (Scopus)
2013
Open Access
27 Citations (Scopus)
Open Access
25 Citations (Scopus)
Open Access
14 Citations (Scopus)

Insulin-Releasing Peptides

Ojo, OO., Flatt, P., Abdel-Wahab, Y. & Conlon, JM., 2013, Handbook of Biologically Active Peptides (2nd Edition). Elsevier, p. 364-370

Research output: Chapter in Book/Report/Conference proceedingChapter

2011
Open Access
18 Citations (Scopus)

Peptidomic analysis of skin secretions from the bullfrog Lithobates catesbeianus (Ranidae) identifies multiple peptides with potent insulin-releasing activity

Mechkarska, M., Ojo, O. O., Meetani, M. A., Coquet, L., Jouenne, T., Abdel-Wahab, Y., Flatt, P., King, J. D. & Conlon, J. M., Feb 2011, In : Peptides. 32, 2, p. 203-208

Research output: Contribution to journalArticle

Open Access
27 Citations (Scopus)
Open Access
32 Citations (Scopus)