Personal profile
Biography
I am a research associate in microbial biotechnology working within the Pharmacy and Pharmaceutical Sciences research centre at Ulster University. I have interests and expertise in molecular microbiology, microbial biotechnology, and antimicrobial resistance. In addition to my research portfolio, I have significant experience in the commercialisation of microbial biotechnology. I am currently focused on two research projects; The Tolerate EU Project and STAMPs.
The Tolerate EU Project is a Horizon Europe consortium project investigating if microbial genes and taxa identified in ancient DNA samples dating back up to 600,000 years can be utilised for the bioaugmentation of agricultural crops to mitigate the effects of climate change (https://tolerate-eu-project.com/).
STAMPs is a Invest NI funded Proof of Concept study where I am a research co-investigator. The project is focusing on the development of a novel sensitiser-peptide conjugates developed at Ulster University for application initially in skin infections such as diabetic foot ulceration. This project has been spun out of work I carried out as part of the EPSRC funded program grant “Beyond Antibiotics” being run in collaboration with The University of Oxford, University College London, and several commercial partners.
Prior to becoming involved with my current projects I led projects investigating microbial biosurfactant technology with regards to applications in food technology, cosmetics, and biomedical applications such as antimicrobial and anti-cancer therapeutics. Before joining Ulster University, I led a Knowledge Transfer Partnership (KTP) at Queen’s University Belfast, UK investigating microbial driven inflammatory lung disease. I did my Ph.D. in the field of marine microbiology and quorum sensing at The University of Nottingham, UK.
Education/Academic qualification
PhD, The Signal Based Relationship between the Green Seaweed Ulva and its Indigenous Bacterial Community, University of Nottingham
Sept 2008 → Sept 2012
Award Date: 1 Jun 2016
Master, Molecular Medical Microbiology , University of Nottingham
Sept 2007 → Sept 2008
Award Date: 1 Dec 2008
Bachelor, Biochemistry and Microbiology, King's College London
Sept 2003 → Jul 2006
Award Date: 1 Jun 2006
External positions
Honorary Research Associate , Queens University Belfast
Apr 2016 → Aug 2016
Knowledge Transfer Partnership Associate , Queens University Belfast
Apr 2013 → Apr 2016
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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SDG 7 Affordable and Clean Energy
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SDG 9 Industry, Innovation, and Infrastructure
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SDG 13 Climate Action
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SDG 14 Life Below Water
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SDG 15 Life on Land
Fingerprint
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Collaborations and top research areas from the last five years
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Anti-biofilm Activity of Novel Sensitiser Peptide Conjugates
McMullan, E., Twigg, M., Puyol McKenna, P., Taggart, M., McHale, A. P. & Callan, J., 11 Jun 2025, (Unpublished).Research output: Contribution to conference › Poster › peer-review
File20 Downloads (Pure) -
The Application of Glycolipid-Type Microbial Biosurfactants as Active Pharmaceutical Ingredients for the Treatment and Prevention of Cancer
McMahon, A., Twigg, M., Marchant, R. & Banat, I. M., 31 May 2025, In: Pharmaceuticals. 18, 5, p. 1-19 19 p., 676.Research output: Contribution to journal › Review article › peer-review
Open AccessFile25 Downloads (Pure) -
The Effect of Green Tea and Chlorhexidine on Porphyromonas gingivalis
Najmi, Y., Ternan, N. G., McCarron, P. A., Pisani, F., Twigg, M., Osman, A. & Seoudi, N., 27 Jun 2025, (Unpublished).Research output: Contribution to conference › Poster › peer-review
File14 Downloads (Pure) -
Anti-biofilm Activity of Novel Sensitiser Peptide Conjugates
McMullan, E., Twigg, M., Taggart, M., McHale, A. P. & Callan, J., 28 Jun 2024, (Unpublished).Research output: Contribution to conference › Poster › peer-review
File8 Downloads (Pure) -
Characterisation of cytotoxicity and immunomodulatory effects of glycolipid biosurfactants on human keratinocytes
Adu, S., Twigg, M., Naughton, P., Marchant, R. & Banat, I. M., Jan 2023, In: Applied Microbiology and Biotechnology. 107, 1, p. 137-152 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile55 Link opens in a new tab Citations (Scopus)94 Downloads (Pure)
Activities
- 5 Oral presentation
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Two birds, one stone: The antimicrobial enhancing and microbiome protective bioactivities of glycolipid-type biosurfactants.
Twigg, M. (Speaker), Marchant, R. (Contributor), Naughton, P. (Contributor) & Banat, I. (Contributor)
11 Sept 2025Activity: Talk or presentation › Oral presentation
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Beyond Antibiotics: Photo/ Sono-dynamic Therapy as a Treatment for Bacterial Infection
Twigg, M. (Speaker), McHale, A. (Contributor) & Callan, J. (Contributor)
31 May 2023Activity: Talk or presentation › Oral presentation
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Glycolipid biosurfactants as novel anti-cancer agents.
Twigg, M. (Speaker)
29 Sept 2022Activity: Talk or presentation › Oral presentation
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Surfactants from the sea: Rhamnolipid production by marine bacteria
Twigg, M. (Speaker)
9 Apr 2019Activity: Talk or presentation › Oral presentation
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A Critical Evaluation of Experimental Evidence Required for the Identification of Biosurfactant Producing Bacteria.
Twigg, M. (Speaker)
26 Sept 2019Activity: Talk or presentation › Oral presentation
Profiles
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Sensitiser Tethered Antimicrobial Peptides (STAMPs): A new sub-class of broad spectrum antibiotic.
Callan, J. (PI), Twigg, M. (CoI) & Lynch, O. (CoI)
14/03/24 → 30/09/26
Project: Research
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ICURE Discover STAMPs: A new sub-class of broad spectrum antibiotic
Callan, J. (PI), Twigg, M. (CoI) & Puyol McKenna, P. (CoI)
8/01/26 → 12/03/26
Project: Research
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iCure Sustainable natural glycolipids for healthcare
Banat, I. (PI), Macrae, J. (CoI) & Twigg, M. (CoI)
1/07/21 → 31/10/21
Project: Research