• Cromore Road, Coleraine Campus

    BT52 1SA Coleraine

    United Kingdom

  • 77 Citations
  • 4 h-Index
20132019
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Personal profile

Biography

I am currently a research associate in biotechnology working within the Biomedical Sciences Research Institute at Ulster University. I have interests and expertise in molecular microbiology, marine microbiology and microbial biotechnology. I am currently working on the MARISURF project, a Horizon 2020 funded consortium investigating biosurfactant production by marine bacteria. It is the aim of the project to identify biosurfactants which can be exploited for biotechnological applications in various industrial sector acting as more environmentally sustainable alternatives to chemically derived surfactants. I received my Ph.D. from the University of Nottingham where, working in collaboration with Plymouth Marine Laboratory, I investigated the interactions between marine algal species and their indigenous, epiphytic bacterial communities. My doctoral research demonstrated for the first time that bacteria influence the germination of the seaweed Ulva via quorum sensing signalling molecules. After completing my Ph.D. in 2012 I carried out a three-year industrially funded postdoctoral research project at Queen’s University Belfast investigating a novel biomarker for the detection of bacterial driven exacerbation in cystic fibrosis patients and the role bacterial infection plays in the protease/ anti-protease homeostatic balance within these patients.

Education/Academic qualification

PhD, University of Nottingham

Sep 2008Sep 2012

Master, University of Nottingham

Sep 2007Sep 2008

Bachelor, King's College London

Sep 2003Jul 2006

External positions

Honorary Research Associate , Queen's University Belfast

Apr 2016Aug 2016

Knowledge Transfer Partnership Associate , Queen's University Belfast

Apr 2013Apr 2016

Fingerprint Dive into the research topics where Matthew Twigg is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 10 Similar Profiles
Cystic Fibrosis Medicine & Life Sciences
Leukocyte Elastase Medicine & Life Sciences
Secretory Leukocyte Peptidase Inhibitor Medicine & Life Sciences
Sputum Medicine & Life Sciences
Neutrophils Medicine & Life Sciences
Polyhydroxyalkanoates Medicine & Life Sciences
Burkholderia Medicine & Life Sciences
Lung Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2013 2019

  • 77 Citations
  • 4 h-Index
  • 5 Article
  • 1 Poster
  • 1 Literature review

Alginate/Chitosan Particle-Based Drug Delivery Systems for Pulmonary Applications

Hill, M., Twigg, M., Sheridan, E., Hardy, J., Elborn, S., Taggart, C., Scott, C. & Migaud, M., 2 Aug 2019, In : Pharmaceutics. 11, 8, 12 p.

Research output: Contribution to journalArticle

Open Access
File
Tobramycin
Chitosan
Mucus
Drug Delivery Systems
Cystic Fibrosis

Elastase activity on sputum neutrophils correlates with severity of lung disease in cystic fibrosis

Dittrich, S., Kühbandner, I., Gehrig, S., Rickert-Zacharias, V., Twigg, M., Wege, S., Taggart, C., Herth, F., Carsten, S. & Mall, M., 29 Mar 2018, In : European Respiratory Journal. 51, 3, 11 p., 1701910.

Research output: Contribution to journalArticle

Leukocyte Elastase
Pancreatic Elastase
Sputum
Cystic Fibrosis
Lung Diseases
3 Citations (Scopus)
Open Access
File
surface tension
nuclear magnetic resonance
relative abundance
PAH
algal bloom
5 Citations (Scopus)

Enhanced rhamnolipid production in Burkholderia thailandensis transposon knockout strains deficient in polyhydroxyalkanoate (PHA) synthesis

Funston, SJ., Tsaousi, K., Smyth, TJ., Twigg, M., Marchant, R. & Banat, I., 8 Sep 2017, (Accepted/In press) In : Applied Microbiology and Biotechnology. 101

Research output: Contribution to journalArticle

Open Access
File
Polyhydroxyalkanoates
Burkholderia
Pseudomonas aeruginosa
Genes
rhamnolipid

Cleaved SLPI as a marker for exacerbation in cystic fibrosis

Twigg, M., Brockbank, S., Lowery, P., FitzGerald, P., Weldon, S. & Taggart, C., 30 Oct 2015. 1 p.

Research output: Contribution to conferencePoster

Open Access
Secretory Leukocyte Peptidase Inhibitor
Cystic Fibrosis
Leukocyte Elastase
Monoclonal Antibodies
Hybridomas

Activities 2019 2019

  • 1 Oral presentation

Surfactants from the sea: Rhamnolipid production by marine bacteria

Matthew Twigg (Speaker)
9 Apr 2019

Activity: Talk or presentationOral presentation