Research output per year
Research output per year
Personal profile
Biography
My research interests lie in investigating epigenetic regulation in normal development and disease e.g. osteoarthritis and hypertension.
We have a particular focus on the role of DNA methyltransferase enzymes in carrying out faithful transmission of the DNA methylation pattern and their contribution to onset and pathology of disease.
Additionally we are also investigating the influence of environmental factors such as nutrients and xenobiotics on DNA methylation maintenance and reprogramming.
Teaching interests
Diane obtained a Postgraduate Certificate in Higher Education Practice and has been a Fellow of the Higher Education Authority since 2008.She designed and leads the innovative online Postgraduate Diploma Stem Cell Biology programme which was developed with BBSRC Modular Training for Industry funding. For full details of this course see our prospectus page.
Administrative roles
Chairperson for the Royal Society of Biology (2017-2019), N. Ireland Branch
Chair of the judging panel of the Undergraduate Awards Life Sciences section
External positions
Chairperson, Royal Society of Biology NI Branch
2017 → 2019Fingerprint
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Research output
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DNA methylation of hypertension-related genes and effect of riboflavin supplementation in adults stratified by genotype for the MTHFR C677T polymorphism
Amenyah, S., Ward, M., McMahon, A., Deane, J., McNulty, H., Hughes, C., Strain, S., Horigan, G., Purvis, J., Walsh, CP. & Lees Murdock, D., 1 Jan 2021, In: International Journal of Cardiology. 322, p. 233-239 7 p.Research output: Contribution to journal › Article › peer-review
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Effects of maternal folic acid supplementation during the second and third trimesters of pregnancy on neurocognitive development in the child: an 11-year follow-up from a randomised controlled trial
Caffrey, A., McNulty, H., Rollins, M., Prasad, G., Gaur, P., Talcott, J., Witton, C., Cassidy, T., Marshall, B., Dornan, J., Moore, AJ., Ward, M., Strain, S., Molloy, A., McLaughlin, M., Lees Murdock, D., Walsh, CP. & Pentieva, K., 14 Jan 2021, (Accepted/In press) In: BMC Medicine.Research output: Contribution to journal › Article › peer-review
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Influence of Nutrients involved in One-Carbon Metabolism on DNA Methylation in Adults: A Systematic Review and Meta-Analysis
Amenyah, S., Hughes, C., Ward, M., Roxborough, S., Deane, J., Thursby, S-J., Walsh, CP., Kok, D., Strain, S., McNulty, H. & Lees Murdock, D., 31 Aug 2020, In: Nutrition Reviews. 78, 8, p. 647-666 20 p., nuz094.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)86 Downloads (Pure) -
Nutritional Epigenomics and Age-Related Disease
Amenyah, S., Ward, M., Strain, S., McNulty, H., Hughes, C., Dollin, C., Walsh, CP. & Lees Murdock, D., 31 Jul 2020, In: Current developments in nutrition. 4, 7, 16 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile -
Riboflavin supplementation alters global and gene-specific DNA methylation in adults with the MTHFR 677 TT genotype
Amenyah, S., McMahon, A., Ward, M., Deane, J., McNulty, H., Hughes, C., Strain, J. J., Horigan, G., Purvis, J., Walsh, CP. & Lees Murdock, D., 1 Jun 2020, In: Biochimie. 173, p. 17-26 10 p.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus)