• Cromore Road, Coleraine Campus

    BT52 1SA Coleraine

    United Kingdom

  • 514 Citations
  • 9 h-Index

Research output per year

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Personal profile


My research interests lie in investigating epigenetic regulation in normal development and disease e.g. osteoarthritis and hypertension.

We have a particular focus on the role of DNA methyltransferase enzymes in carrying out faithful transmission of the DNA methylation pattern and their contribution to onset and pathology of disease. 

Additionally we are also investigating the influence of environmental factors such as nutrients and xenobiotics on DNA methylation maintenance and reprogramming.

Teaching interests

Diane obtained a Postgraduate Certificate in Higher Education Practice and has been a Fellow of the Higher Education Authority since 2008.She designed and leads the innovative online Postgraduate Diploma Stem Cell Biology programme which was developed with BBSRC Modular Training for Industry funding. For full details of this course see our prospectus page.

Administrative roles

Chairperson for the Royal Society of Biology (2017-2019), N. Ireland Branch

Chair of the judging panel of the Undergraduate Awards Life Sciences section

External positions

Chairperson, Royal Society of Biology NI Branch


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Research Output

  • 514 Citations
  • 9 h-Index
  • 17 Article
  • 3 Chapter
  • 2 Abstract
  • 1 Review article

Influence of Nutrients involved in One-Carbon Metabolism on DNA Methylation in Adults: A Systematic Review and Meta-Analysis

Amenyah, S., Hughes, C., Ward, M., Roxborough, S., Deane, J., Thursby, S-J., Walsh, CP., Kok, D., Strain, S., McNulty, H. & Lees Murdock, D., 23 Jan 2020, In : Nutrition Reviews. 78, 8, p. 647-666 20 p., nuz094.

Research output: Contribution to journalArticle

  • 2 Citations (Scopus)

    Nutritional Epigenomics and Age-Related Disease

    Lees Murdock, D., Ward, M., Strain, S., McNulty, H., Hughes, C., Dollin, C. & Walsh, CP., 6 Jun 2020, In : Current developments in nutrition. 4, 7

    Research output: Contribution to journalReview article

    Open Access
  • 4 Downloads (Pure)

    Riboflavin supplementation alters global and gene-specific DNA methylation in adults with the MTHFR 677 TT genotype

    Amenyah, S., McMahon, A., Ward, M., Deane, J., McNulty, H., Hughes, C., Strain, J. J., Horigan, G., Purvis, J., Walsh, CP. & Lees Murdock, D., 1 Jun 2020, In : Biochimie. 173, p. 17-26 10 p.

    Research output: Contribution to journalArticle

  • 2 Citations (Scopus)
    Open Access
  • 2 Citations (Scopus)
    16 Downloads (Pure)
    Open Access
  • 1 Citation (Scopus)
    64 Downloads (Pure)