Research Output per year
Personal profile
Biography
Research InterestsInvestigating epigenetic regulation in normal development and disease e.g. osteoarthritis and hypertension. Particular focus is on the role of DNA methyltransferase enzymes in carrying out faithful transmission of the DNA methylation pattern and their contribution to onset and pathology of disease.Investigating the influence of environmental factors such as nutrients and xenobiotics on DNA methylation maintenance and reprogramming.Teaching interestsDiane obtained a Postgraduate Certificate in Higher Education Practice and has been a Fellow of the Higher Education Authority since 2008.She designed and leads the innovative online Postgraduate Diploma Stem Cell Biology programme which was developed with BBSRC Modular Training for Industry funding. For full details of this course see our prospectus pageAdministrative rolesDeputy Chairperson for the Royal Society of Biology, N. Ireland BranchChair of the judging panel of the Undergraduate Awards Life Sciences section
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Methylation
Medicine & Life Sciences
DNA Methylation
Medicine & Life Sciences
Folic Acid
Medicine & Life Sciences
Methyltransferases
Medicine & Life Sciences
Germ Cells
Medicine & Life Sciences
Randomized Controlled Trials
Medicine & Life Sciences
DNA
Medicine & Life Sciences
Pregnancy
Medicine & Life Sciences
Network
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Research Output 2003 2019
A randomized controlled trial of folic acid intervention in pregnancy highlights a putative methylation-regulated control element at ZFP57.
Irwin, R. E., Thursby, S-J., Ondicova, M., Pentieva, K., McNulty, H., Richmond, R., Caffrey, A., Lees Murdock, D., McLaughlin, M., CASSIDY, T., Sudderman, M., Relton, C. & Walsh, CP., 18 Feb 2019, 11, 1, 16 p., 31.Research output: Contribution to journal › Article
Open Access
File
Folic Acid
Methylation
Randomized Controlled Trials
Pregnancy
Genetic Promoter Regions
Effect of continued folic acid supplementation beyond the first trimester of pregnancy on cognitive performance in the child: a follow-up study from a randomized controlled trial (FASSTT Offspring trial)
McNulty, H., Rollins, M., Cassidy, T., Caffrey, A., Marshall, B., Dornan, J., McLaughlin, M., McNulty, B. A., Ward, M., Strain, S., Molloy, A. M., Lees Murdock, D. J., Walsh, C. P. & Pentieva, K., 31 Oct 2019, In : BMC Medicine. 17, 1, p. 1-11 11 p., 196.Research output: Contribution to journal › Article
Open Access
File
Third Pregnancy Trimester
Second Pregnancy Trimester
First Pregnancy Trimester
Folic Acid
Randomized Controlled Trials
Folic Acid Supplementation throughout pregnancy: psychological developmental benefits for children
Henry, L-A., Cassidy, T., Cooper, M., Pentieva, K., McNulty, H., Walsh, C. & Lees Murdock, D., 31 Aug 2018, In : Acta Paediatrica. 107, 8, p. 1370-1378 8 p.Research output: Contribution to journal › Article
Open Access
File
Folic Acid
Emotional Intelligence
Psychology
Pregnancy
Mothers
Gene-specific DNA methylation in newborns in response to folic acid supplementation during the second and third trimesters of pregnancy: epigenetic analysis from a randomized controlled trial
Caffrey, A., Irwin, R. E., McNulty, H., Strain, JJ., Lees Murdock, D., McNulty, B., Ward, M., Walsh, C. & Pentieva, K., 9 Apr 2018, In : American Journal of Clinical Nutrition. 107, 4, p. 566-575 9 p.Research output: Contribution to journal › Article
Open Access
File
Third Pregnancy Trimester
Second Pregnancy Trimester
DNA Methylation
Folic Acid
Epigenomics
Impact of folic acid supplementation during pregnancy on cognitive performance of children at age 11 years: preliminary results from the FASSTT Offspring study
Caffrey, A., McNulty, H., Irwin, R. E., CASSIDY, T., McLaughlin, M., Lees Murdock, D., Walsh, CP. & Pentieva, K., 6 Sep 2018.Research output: Contribution to conference › Abstract