Research Output per year
Personal profile
Biography
My research interests lie in investigating epigenetic regulation in normal development and disease e.g. osteoarthritis and hypertension.
We have a particular focus on the role of DNA methyltransferase enzymes in carrying out faithful transmission of the DNA methylation pattern and their contribution to onset and pathology of disease.
Additionally we are also investigating the influence of environmental factors such as nutrients and xenobiotics on DNA methylation maintenance and reprogramming.
Teaching interests
Diane obtained a Postgraduate Certificate in Higher Education Practice and has been a Fellow of the Higher Education Authority since 2008.She designed and leads the innovative online Postgraduate Diploma Stem Cell Biology programme which was developed with BBSRC Modular Training for Industry funding. For full details of this course see our prospectus page.
Administrative roles
Chairperson for the Royal Society of Biology (2017-2019), N. Ireland Branch
Chair of the judging panel of the Undergraduate Awards Life Sciences section
External positions
Chairperson, Royal Society of Biology NI Branch
2017 → 2019Fingerprint Dive into the research topics where Diane Lees Murdock is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Research Output
Influence of Nutrients involved in One-Carbon Metabolism on DNA Methylation in Adults: A Systematic Review and Meta-Analysis
Amenyah, S., Hughes, C., Ward, M., Roxborough, S., Deane, J., Thursby, S-J., Walsh, CP., Kok, D., Strain, S., McNulty, H. & Lees Murdock, D., 23 Jan 2020, In : Nutrition Reviews. p. 1-20 20 p., nuz094.Research output: Contribution to journal › Article
A randomized controlled trial of folic acid intervention in pregnancy highlights a putative methylation-regulated control element at ZFP57
Irwin, R. E., Thursby, S-J., Ondicova, M., Pentieva, K., McNulty, H., Richmond, R., Caffrey, A., Lees Murdock, D., McLaughlin, M., CASSIDY, T., Sudderman, M., Relton, C. & Walsh, CP., 18 Feb 2019, In : Clinical Epigenetics. 11, p. 1-16 16 p., 31.Research output: Contribution to journal › Article
Open Access
File
2
Citations
(Scopus)
13
Downloads
(Pure)
Effect of continued folic acid supplementation beyond the first trimester of pregnancy on cognitive performance in the child: a follow-up study from a randomized controlled trial (FASSTT Offspring trial)
McNulty, H., Rollins, M., Cassidy, T., Caffrey, A., Marshall, B., Dornan, J., McLaughlin, M., McNulty, B. A., Ward, M., Strain, S., Molloy, A. M., Lees Murdock, D. J., Walsh, C. P. & Pentieva, K., 31 Oct 2019, In : BMC Medicine. 17, 1, p. 1-11 11 p., 196.Research output: Contribution to journal › Article
Open Access
File
Folic Acid Supplementation throughout pregnancy: psychological developmental benefits for children
Henry, L-A., Cassidy, T., Cooper, M., Pentieva, K., McNulty, H., Walsh, C. & Lees Murdock, D., 31 Aug 2018, In : Acta Paediatrica. 107, 8, p. 1370-1378 8 p.Research output: Contribution to journal › Article
Open Access
File
6
Citations
(Scopus)
56
Downloads
(Pure)
Gene-specific DNA methylation in newborns in response to folic acid supplementation during the second and third trimesters of pregnancy: epigenetic analysis from a randomized controlled trial
Caffrey, A., Irwin, R. E., McNulty, H., Strain, JJ., Lees Murdock, D., McNulty, B., Ward, M., Walsh, C. & Pentieva, K., 9 Apr 2018, In : American Journal of Clinical Nutrition. 107, 4, p. 566-575 10 p.Research output: Contribution to journal › Article
Open Access
File
17
Citations
(Scopus)
54
Downloads
(Pure)
Thesis
Epigenetic effects of riboflavin supplementation on hypertension in adults screened for the MTHFR C677T polymorphism
Author: Amenyah, S., May 2020Supervisor: Lees Murdock, D. (Supervisor) & Ward, M. (Supervisor)
Student thesis: Doctoral Thesis