Research output per year
Research output per year
- 1 - 50 out of 75 results
Search results
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2023
College Student Mental Health and Wellbeing Prior to and during the COVID-19 Pandemic
McLafferty, M., Ward, C., Walsh, C. P., O'Neill, S., Bjourson, T., McHugh, R., Brown, N., McBride, L., Brady, J. & Murray, EK., 18 Nov 2023, In: Education Sciences . 13, 11, p. 1-12 12 p., 1154.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Epigenetic effects of folate and related B vitamins on brain health throughout life: Scientific substantiation and translation of the evidence for health-improvement strategies
Caffrey, A., Lamers, Y., Murphy, M. M., Letourneau, N., Irwin, R. E., Pentieva, K., Ward, M., Tan, A., Rojas-Gomez, A., Rovira i Virgili, U., Canals, J., Leung, B. MY., Bell, R., Giesbrecht, G. F., Dewey, D., Field, C. J., Kobor, M., Walsh, CP. & McNulty, H., 21 Feb 2023, (Published online) Nutrition Bulletin, 48, 2, p. 267-277 11 p.Research output: Contribution to specialist publication › Article
Open AccessFile46 Downloads (Pure) -
Exercise is associated with younger methylome and transcriptome profiles in human skeletal muscle
Voisin, S., Seale, K., Macsue, J., Landen, S., Harvey, N., Haupt, L., Griffiths, L., Ashton, K., Coffey, V., Thompson, J-L., Doering, T., Lindholm, M., Walsh, C., Davison, G., Irwin, R., McBride, C., Hansson, O., Asplund, O., Heikkinen, A., Piirila, P., & 7 others, 2 May 2023, (Published online) In: Aging Cell. p. 1-15 15 p., e13859.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)20 Downloads (Pure) -
STING activation in TET2-mutated hematopoietic stem/progenitor cells contributes to the increased self-renewal and neoplastic transformation
Xie, J., Sheng, M., Rong, S., Zhou, D., Wang, C., Wu, W., Huang, J., Sun, Y., Wang, Y., Chen, P., Wu, Y., Wang, Y., Wang, L., Zhou, B. O., Huang, X., Walsh, C. P., Bohlander, S. K., Huang, J., Wang, X., Xu, G-L., & 2 others, 10 Oct 2023, (Published online) In: Leukemia. 37, 12, p. 2457-2467 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Downloads (Pure) -
The UHRF1 protein is a key regulator of retrotransposable elements and innate immune response to viral RNA in human cells
Irwin, R. E., Scullion, C., Thursby, S-J., Sun, M-L., Thakur, A., Hilman, L., Callaghan, B., Thompson, P., McKenna, D. J., Rothbart, S., Xu, G-L. & Walsh, CP., 29 May 2023, (Published online) In: Epigenetics. 18, 1, p. 1-18 19 p., 2216005 .Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)4 Downloads (Pure) -
2022
Folic acid intervention during pregnancy alters DNA methylation, affecting neural target genes through two distinct mechanisms
Ondičová, M., Irwin, R. E., Thursby, S-J., Hilman, L., Caffrey, A., Cassidy, T., McLaughlin, M., Lees-Murdock, D. J., Ward, M., Murphy, M., Lamers, Y., Pentieva, K., McNulty, H. & Walsh, C. P., 16 May 2022, (Published online) In: Clinical Epigenetics. 14, 1, 20 p., 63 (2022).Research output: Contribution to journal › Article › peer-review
Open AccessFile13 Citations (Scopus)21 Downloads (Pure) -
Loss of TET reprograms Wnt signaling through impaired demethylation to promote lung cancer development
Xu, Q., Wang, C., Zhou, J-X., Xu, Z-M., Gao, J., Sui, P., Walsh, C. P., Ji, H. & Xu, G-L., 2 Feb 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 6, p. 1-12 12 p., e2107599119.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Citations (Scopus)52 Downloads (Pure) -
Prognostic value of miR-21 for prostate cancer: a systematic review and meta-analysis
Stafford, MY. C., Willoughby, C. E., Walsh, C. P. & McKenna, D. J., 11 Jan 2022, In: Bioscience Reports. 42, 1, p. 1-19 19 p., BSR20211972.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)27 Downloads (Pure) -
Suicidal behaviours and mental health disorders among students commencing college
Ward, C., Mc Lafferty, M., McLaughlin, J., Mc Hugh, R., McBride, L., Brady, J., Bjourson, AJ., Walsh, CP., O'Neill, S. & Murray, EK., 31 Jan 2022, In: Psychiatry research. 307, p. 1-7 7 p., 114314.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)17 Downloads (Pure) -
The Mediating Roles of Mental Health and Substance Use on Suicidal Behavior Among Undergraduate Students With ADHD
Brown, N., Mc Lafferty, M., O'Neill, S., Mc Hugh, R., Ward, C., McBride, L., Brady, J., Bjourson, AJ., Walsh, CP. & Murray, EK., 1 Sept 2022, In: Journal of Attention Disorders. 26, 11, p. 1437-1451 15 p., 10870547221075844.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)96 Downloads (Pure) -
Variations in psychological disorders, suicidality, and help-seeking behaviour among college students from different academic disciplines
McLafferty, M., Brown, N., Brady, J., McLaughlin, J., McHugh, R., Ward, C., McBride, L., Bjourson, A. J., O’Neill, S. M., Walsh, C. P., Murray, E. K. & Chupradit, S. (ed.), 30 Dec 2022, In: PLoS ONE. 17, 12, p. 1-17 17 p., e0279618.Research output: Contribution to journal › Article › peer-review
Open AccessFile42 Downloads (Pure) -
2021
Depression, anxiety and suicidal behaviour among college students: Comparisons pre-COVID-19 and during the pandemic
Mc Lafferty, M., Brown, N., Mc Hugh, R., Ward, C., Stevenson, A., McBride, L., Brady, J., Bjourson, AJ., O'Neill, S., Walsh, CP. & Murray, EK., 31 Dec 2021, In: Psychiatry Research Communications. 1, 2, p. 1-19 19 p., PSYCOM_100012.Research output: Contribution to journal › Article › peer-review
Open AccessFile26 Citations (Scopus)122 Downloads (Pure) -
DNA methylation of hypertension-related genes and effect of riboflavin supplementation in adults stratified by genotype for the MTHFR C677T polymorphism
Amenyah, S., Ward, M., McMahon, A., Deane, J., McNulty, H., Hughes, C., Strain, J. J., Horigan, G., Purvis, J., Walsh, CP. & Lees Murdock, D., 1 Jan 2021, In: International Journal of Cardiology. 322, p. 233-239 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Citations (Scopus)81 Downloads (Pure) -
Effects of maternal folic acid supplementation during the second and third trimesters of pregnancy on neurocognitive development in the child: an 11-year follow-up from a randomised controlled trial
Caffrey, A., McNulty, H., Rollins, M., Prasad, G., Gaur, P., Talcott, J., Witton, C., Cassidy, T., Marshall, B., Dornan, J., Moore, AJ., Ward, M., Strain, JJ., Molloy, A., McLaughlin, M., Lees-Murdock, D., Walsh, CP. & Pentieva, K., 10 Mar 2021, (Published online) In: BMC Medicine. 19, 1, 13 p., 73.Research output: Contribution to journal › Article › peer-review
Open AccessFile23 Citations (Scopus)81 Downloads (Pure) -
Low birth weight female piglets show altered intestinal development, gene expression, and epigenetic changes at key developmental loci
Ayuso, M., Irwin, R., Walsh, C., Van Cruchten, S. & Van Ginneken, C., 18 Mar 2021, In: FASEB JOURNAL. 35, 4, e21522.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)13 Downloads (Pure) -
2020
CandiMeth: Powerful yet simple visualization and quantification of DNA methylation at candidate genes
Thursby, S-J., Lobo, D., Pentieva, K., Zhang, S-D., Irwin, R. E. & Walsh, CP., 22 Jun 2020, In: GigaScience. 9, 6, p. 1-14 14 p., giaa066.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)214 Downloads (Pure) -
Methylome profiling of young adults with depression supports a link with immune response and psoriasis
Lapsley, C., Irwin, R. E., Mc Lafferty, M., Thursby, S-J., O'Neill, S., Bjourson, AJ., Walsh, CP. & Murray, EK., 2 Jul 2020, In: Clinical Epigenetics. 12, 1, 16 p., 85.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)95 Downloads (Pure) -
miR‐210 is induced by hypoxia and regulates neural cell adhesion molecule in prostate cells
Angel, C. Z., Lynch, S. M., Nesbitt, H., McKenna, M. M., Walsh, CP. & McKenna, D. J., 9 Jun 2020, In: Journal of Cellular Physiology. 235, 9, p. 6194-6203 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)132 Downloads (Pure) -
Riboflavin supplementation alters global and gene-specific DNA methylation in adults with the MTHFR 677 TT genotype
Amenyah, S., McMahon, A., Ward, M., Deane, J., McNulty, H., Hughes, C., Strain, J. J., Horigan, G., Purvis, J., Walsh, CP. & Lees Murdock, D., 1 Jun 2020, In: Biochimie. 173, p. 17-26 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Citations (Scopus)224 Downloads (Pure) -
2019
A randomized controlled trial of folic acid intervention in pregnancy highlights a putative methylation-regulated control element at ZFP57
Irwin, R. E., Thursby, S-J., Ondicova, M., Pentieva, K., McNulty, H., Richmond, R., Caffrey, A., Lees Murdock, D., McLaughlin, M., CASSIDY, T., Sudderman, M., Relton, C. & Walsh, CP., 18 Feb 2019, In: Clinical Epigenetics. 11, p. 1-16 16 p., 31.Research output: Contribution to journal › Article › peer-review
Open AccessFile32 Citations (Scopus)75 Downloads (Pure) -
Effect of continued folic acid supplementation beyond the first trimester of pregnancy on cognitive performance in the child: a follow-up study from a randomized controlled trial (FASSTT Offspring trial)
McNulty, H., Rollins, M., Cassidy, T., Caffrey, A., Marshall, B., Dornan, J., McLaughlin, M., McNulty, B. A., Ward, M., Strain, J. J., Molloy, A. M., Lees Murdock, D. J., Walsh, C. P. & Pentieva, K., 31 Oct 2019, (Published online) In: BMC Medicine. 17, 1, p. 1-11 11 p., 196.Research output: Contribution to journal › Article › peer-review
Open AccessFile41 Citations (Scopus)195 Downloads (Pure) -
Hepatocyte Nuclear Factor 4-Alpha Is Essential for the Active Epigenetic State at Enhancers in Mouse Liver
Thakur, A., Wong, J. C. H., Wang, E. Y., Lotto, J., Kim, D., Cheng, J. C., Mingay, M., Cullum, R., Moudgil, V., Ahmed, N., Tsai, S. H., Wei, W., Walsh, C. P., Stephan, T., Bilenky, M., Fuglerud, B. M., Karimi, M. M., Gonzalez, F. J., Hirst, M. & Hoodless, P. A., 8 Oct 2019, In: Hepatology. 70, 4, p. 1360-1376 17 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile40 Citations (Scopus)128 Downloads (Pure) -
The bovine alveolar macrophage DNA methylome is resilient to infection with Mycobacterium bovis
O’Doherty, A. M., Rue-Albrecht, K. C., Magee, D. A., Ahting, S., Irwin, R. E., Hall, T. J., Browne, J. A., Nalpas, N. C., Walsh, C. P., Gordon, S. V., Wojewodzic, M. W. & MacHugh, D. E., 6 Feb 2019, In: Scientific Reports. 9, 1, 15 p., 1510 (2019).Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)61 Downloads (Pure) -
2018
Comparison of DNMT1 inhibitors by methylome profiling identifies unique signature of 5-aza-2'deoxycytidine
Mackin, S-J., O'Neill, K. & Walsh, CP., 2 Aug 2018, In: Epigenomics. 10, 8, p. 1085-1101 16 p.Research output: Contribution to journal › Article › peer-review
8 Citations (Scopus) -
Depletion of DNMT1 in differentiated human cells highlights key classes of sensitive genes and an interplay with polycomb repression
O'Neill, K. M., Irwin, R. E., Mackin, S. J., Thursby, S. J., Thakur, A., Bertens, C., Masala, L., Loughery, J. E. P., McArt, D. G. & Walsh, C. P., 29 Mar 2018, In: Epigenetics and Chromatin. 11, 1, p. 1-21 21 p., 12.Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Citations (Scopus)52 Downloads (Pure) -
Folic Acid Supplementation throughout pregnancy: psychological developmental benefits for children
Henry, L-A., Cassidy, T., McLaughlin, M., Pentieva, K., McNulty, H., Walsh, C. & Lees Murdock, D., 13 Jul 2018, In: Acta Paediatrica. 107, 8, p. 1370-1378 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Citations (Scopus)229 Downloads (Pure) -
Gene-specific DNA methylation in newborns in response to folic acid supplementation during the second and third trimesters of pregnancy: epigenetic analysis from a randomized controlled trial
Caffrey, A., Irwin, R. E., McNulty, H., Strain, JJ., Lees Murdock, D., McNulty, B., Ward, M., Walsh, C. & Pentieva, K., 9 Apr 2018, In: American Journal of Clinical Nutrition. 107, 4, p. 566-575 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile75 Citations (Scopus)120 Downloads (Pure) -
Intragenic sequences in the trophectoderm harbour the greatest proportion of methylation errors in day 17 bovine conceptuses generated using assisted reproductive technologies
O'Doherty, A. M., McGettigan, P., Irwin, R. E., Magee, D. A., Gagne, D., Fournier, E., Al-Naib, A., Sirard, M. A., Walsh, C. P., Robert, C. & Fair, T., 5 Jun 2018, In: BMC Genomics. 19, 1, p. 1-15 15 p., 438 (2018).Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Citations (Scopus)42 Downloads (Pure) -
Investigating the link between miR-210 and hypoxia in prostate cancer.
angel, Z., Walsh, C. & McKenna, D., 1 Jan 2018, In: Ulster Medical Journal. 87, 1, p. 64-64Research output: Contribution to journal › Article › peer-review
Open AccessFile126 Downloads (Pure) -
2017
Identifying clinically relevant imprinted gDMRs sensitive to a transient loss of DNA methylation in human differentiated cells
Mackin, S-J., O'Neill, K. M., Irwin, R. E. & Walsh, C. P., 6 Feb 2017, (Published online) In: The Ulster Medical Journal. 86, 1, p. 55-68Research output: Contribution to journal › Article › peer-review
Open AccessFile21 Downloads (Pure) -
2016
Exposure of bovine oocytes and embryos to elevated non-esterified fatty acid concentrations: integration of epigenetic and transcriptomic signatures in resultant blastocysts.
Desmet, K. L. J., Van Hoeck, V., Gagné, D., Fournier, E., Thakur, A., O' Doherty, A. M., Walsh, CP., Sirad, M. A., Bols, P. E. J. & Leroy, J. L. M. R., 8 Dec 2016, In: BMC Genomics. 17, 1004, p. 1-18Research output: Contribution to journal › Article › peer-review
Open AccessFile69 Citations (Scopus)43 Downloads (Pure) -
miR-24 regulates CDKN1B/p27 expression in prostate cancer.
Lynch, S. M., McKenna, M. M., Walsh, C. & McKenna, D. J., 5 Feb 2016, In: The Prostate. 76, 7, p. 637-648 11 p.Research output: Contribution to journal › Article › peer-review
Open Access47 Citations (Scopus) -
Regulation of miR-200c and miR-141 by methylation in prostate cancer
Lynch, S., O'Neill, K. M., McKenna, M. M., Walsh, CP. & McKenna, D. J., 15 Sept 2016, In: The Prostate. 76, 13, p. 1146-1159Research output: Contribution to journal › Article › peer-review
Open AccessFile57 Citations (Scopus)43 Downloads (Pure) -
Regulation of miR-200c and miR-141 by methylation in prostate cancer.
Lynch, S., O'Neill, K., McKenna, M., Walsh, C. & McKenna, D., 9 Sept 2016, (Accepted/In press) In: Ulster Medical Journal, The. 87, 1, p. 11-12Research output: Contribution to journal › Article › peer-review
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The interplay between DNA methylation, folate and neurocognitive development
Irwin, R., Pentieva, K., Cassidy, T., Lees Murdock, D., McLaughlin, M., Prasad, G., McNulty, H. & Walsh, CP., 20 Jun 2016, In: Epigenomics. 8, 6, p. 863-879 16 p.Research output: Contribution to journal › Article › peer-review
Open Access58 Citations (Scopus) -
The role of miR-210 in Prostate Cancer tumour development
McElhatton, N., Walsh, C. & McKenna, D., 9 Sept 2016, (Accepted/In press) In: Ulster Medical Journal, The. 87, 1, p. 13-13Research output: Contribution to journal › Article › peer-review
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Widespread recovery of methylation at gametic imprints in hypomethylated mouse stem cells following rescue with DNMT3A2
Thakur, A., Mackin, S-J., Irwin, R., O’Neill, K. M., Pollin, G. & Walsh, C. P., 22 Nov 2016, In: Epigenetics and Chromatin. 9, 1, p. 1-15 15 p., 53.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)31 Downloads (Pure) -
2015
miR-24 regulates p27 expression in prostate cancer
Lynch, S., McKenna, M., Walsh, C. & McKenna, D., Oct 2015, In: Ulster Medical Journal. 84, 3, p. 208-209Research output: Contribution to journal › Article › peer-review
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2014
5-Hydroxymethylation marks a class of neuronal gene regulated by intragenic methylcytosine levels.
Irwin, R., Thakur, A., O'Neill, K. & Walsh, CP., Nov 2014, In: Genomics. 104, 5, p. 383-92 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile25 Citations (Scopus)39 Downloads (Pure) -
Active and Passive Demethylation of Male and Female Pronuclear DNA in the Mammalian Zygote
Guo, F., Li, X., Liang, D., Li, T., Zhu, P., Guo, H., Wu, X., Wen, L., Gu, T-P., Hu, B., Walsh, C., Li, J., Tang, F. & Xu, G-L., 11 Sept 2014, In: Cell Stem Cell. 15, 4, p. 447-459 12 p.Research output: Contribution to journal › Article › peer-review
281 Citations (Scopus) -
Efficient Translation of Dnmt1 Requires Cytoplasmic Polyadenylation and Musashi Binding Elements
Rutledge, C. E., Lau, H-T., Mangan, H., Hardy, L. L., Sunnotel, O., Guo, F., MacNicol, A. M., Walsh, C. & Lees Murdock, D., 20 Feb 2014, In: PLoS ONE. 9, 2, e88385.Research output: Contribution to journal › Article › peer-review
Open Access21 Citations (Scopus) -
Enzymatic DNA oxidation: mechanisms and biological significance
Xu, G-L. & Walsh, C., 1 Nov 2014, (Accepted/In press) In: BMB Reports. 47, 11, p. 609-618Research output: Contribution to journal › Article › peer-review
Open Access20 Citations (Scopus) -
Genomics Special Issue on 5-hydroxymethylation
Xu, G. & Walsh, CP., 1 Nov 2014, (Accepted/In press) In: Genomics. 104, 5, p. 313Research output: Contribution to journal › Article › peer-review
Open Access -
How to build your own island
Walsh, C. & Thakur, A., 21 Oct 2014, (Accepted/In press) In: eLife. 3Research output: Contribution to journal › Article › peer-review
Open Access -
Ontogeny, conservation and functional significance of maternally inherited DNA methylation at two classes of non-imprinted genes
Rutledge, C. E., Thakur, A., O'Neill, K., Irwin, R. E., Sato, S., Hata, K. & Walsh, C., 4 Mar 2014, In: Development. 141, 6, p. 1313-1323 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile20 Citations (Scopus)38 Downloads (Pure) -
siRNA Silencing of the Mutant Keratin 12 Allele in Corneal Limbal Epithelial Cells Grown from Patients with Meesmann’s Epithelial Corneal Dystrophy
Courtney, D. G., Atkinson, S. D., Allen, E. H. A., Moore, J. E., Walsh, C. P., Leslie Pedrioli, D. M., MacEwan, C. J., Pellegrini, G., Maurizi, E., Serafini, C., Fantacci, M., Liao, H., Irvine, A. D., McLean, W. H. I. & Moore, C. B. T., 31 May 2014, In: Invest Ophthalmol Vis Sci. 55, 5, p. 3352-3360 8 p.Research output: Contribution to journal › Article › peer-review
26 Citations (Scopus) -
2011
DNA methylation plays an important role in promoter choice and protein production at the mouse Dnmt3L locus
O'Doherty, A. M., Rutledge, C. E., Sato, S., Thakur, A., Lees Murdock, D., Hata, K. & Walsh, C., Aug 2011, In: Developmental Biology. 356, 2, p. 411-420Research output: Contribution to journal › Article › peer-review
Open Access17 Citations (Scopus) -
DNMT1 deficiency triggers mismatch repair defects in human cells through depletion of repair protein levels in a process involving the DNA damage response
Loughery, JE., Dunne, PD., O'Nell, KM., Meehan, RR., McDaid, JR. & Walsh, C., 2011, In: Human Molecular Genetics. 20, 16, p. 3241-3255Research output: Contribution to journal › Article › peer-review
52 Citations (Scopus) -
2010
Alterations in the steroid hormone receptor co-chaperone FKBPL are associated with male infertility: a case-control study.
Sunnotel, O., Walsh, C., Downes, S. & Lagan, K., 8 Mar 2010, In: Reproductive Biology and Endocrinology. 8, 22Research output: Contribution to journal › Article › peer-review
Open AccessFile29 Citations (Scopus)34 Downloads (Pure) -
MLH1 mediates PARP-dependent cell death in response to the methylating agent N-methyl-N-nitrosourea (vol 101, pg 441, 2009)
McDaid, J. R., Loughery, J., Dunne, P., Boyer, J. C., Downes, S., Farber, R. A. & Walsh, C., Mar 2010, In: BRITISH JOURNAL OF CANCER. 102, 6, p. 1080Research output: Contribution to journal › Article › peer-review
Open Access