• Cromore Road, Coleraine Campus

    BT52 1SA Coleraine

    United Kingdom

  • 2578 Citations
  • 24 h-Index
1993 …2020

Research output per year

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Personal profile


Professor Colin Willoughby, BSc (Hons), FRCOphth, MD

Professor Colin Willoughby was appointed as Professor of Ophthalmology at Ulster University and an Honorary Consultant Ophthalmic Surgeon in the Belfast Health and Social Care Trust in January 2018. The main aim of his research is to improve the understanding, diagnosis and treatment of two major worldwide blinding disorders:  corneal blindness and glaucoma.  He has specific interests in developing novel molecular, pharmacological and cellular therapies for glaucoma and anterior segment disease and uses a number of state-of-the-art genomic technologies. 

He attended medical school at the University of Liverpool, qualifying in 1988 with a BSc First Class in Anatomy, and a Bachelor of Medicine and Surgery with Honours (MBChB Hons) in 1991. He commenced ophthalmology clinical training in 1993 in Liverpool and obtained the Fellowship of the Royal College of Ophthalmologists (FRCOphth) in 1996. Having spent two years in the Hospital for Sick Children, Toronto, he then became Lecturer in Ophthalmology at the University of Liverpool. He returned to Northern Ireland in 2004 and was a Senior Lecturer in Ophthalmology, Queen’s University Belfast.  In 2013 he was appointed Professor of Ophthalmology in the University of Liverpool and an Honorary Consultant Ophthalmic Surgeon in St. Paul’s Eye Unit, Royal Liverpool University Hospital with a clinical and surgical practice in glaucoma, cornea, genetics and general ophthalmology.

Prof Colin Willoughby is an Editorial Board Member (Glaucoma) for Graefe's Archive for Clinical and Experimental Ophthalmology. 

External positions

Honorary Professor of Ophthalmology, University of Liverpool

1 Jan 2018 → …

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Research Output

  • 2578 Citations
  • 24 h-Index
  • 88 Article
  • 1 Chapter
  • 1 Letter

An intraocular pressure polygenic risk score stratifies multiple primary open angle glaucoma parameters including treatment intensity

Qassim, A., Souzeau, E., Siggs, O. M., Hassall, M. M., Han, X., Griffiths, H. L., Frost, N. A., Vallabh, N. A., Kirwan, J. F., Menon, G., Cree, A. J., Galanopoulos, A., Agar, A., Healey, P. R., Graham, S. L., Landers, J., Casson, R. J., Gharahkhani, P., Willoughby, C., Hewitt, A. W. & 3 others, Lotery, A. J., MacGregor, S. & Craig, J. E., 7 Jan 2020, In : OPHTHALMOLOGY.

Research output: Contribution to journalArticle

  • 1 Citation (Scopus)

    Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression

    Craig, J. E., Han, X., Qassim, A., Hassall, M., Cooke Bailey, J. N., Kinzy, T. G., Khawaja, A. P., An, J., Marshall, H., Gharahkhani, P., Igo, R. P., Graham, S. L., Healey, P. R., Ong, J., Zhou, T., Siggs, O., Law, M. H., Souzeau, E., Ridge, B., Hysi, P. G. & 39 others, Burdon, K. P., Mills, R. A., Landers, J., Ruddle, J. B., Agar, A., Galanopoulos, A., White, A. J. R., Willoughby, C. E., Andrew, N. H., Best, S., Vincent, A. L., Goldberg, I., Radford-smith, G., Martin, N. G., Montgomery, G. W., Vitart, V., Hoehn, R., Wojciechowski, R., Jonas, J. B., Aung, T., Pasquale, L. R., Cree, A. J., Sivaprasad, S., Vallabh, N. A., Viswanathan, A. C., Pasutto, F., Haines, J. L., Klaver, C. C. W., Van Duijn, C. M., Casson, R. J., Foster, P. J., Khaw, P. T., Hammond, C. J., Mackey, D. A., Mitchell, P., Lotery, A. J., Wiggs, J. L., Hewitt, A. W. & Macgregor, S., 20 Jan 2020, In : Nature Genetics. 52, 2, p. 160-166 7 p.

    Research output: Contribution to journalArticle

  • 2 Citations (Scopus)
    Open Access
  • 3 Citations (Scopus)
    11 Downloads (Pure)

    Association of Genetic Variation with Keratoconus

    McComish, B. J., Sahebjada, S., Bykhovskaya, Y., Willoughby, C. E., Richardson, A. J., Tenen, A., Charlesworth, J. C., MacGregor, S., Mitchell, P., Lucas, S. E. M., Mills, R. A., MacKey, D. A., Li, X., Wang, J. J., Jensen, R. A., Rotter, J. I., Taylor, K. D., Hewitt, A. W., Rabinowitz, Y. S., Baird, P. N. & 2 others, Craig, J. E. & Burdon, K. P., 19 Dec 2019, In : JAMA Ophthalmology.

    Research output: Contribution to journalArticle

  • Bandage contact lens and topical steroids are risk factors for the development of microbial keratitis after epithelium-off CXL

    Tzamalis, A., Romano, V., Cheeseman, R., Vinciguerra, R., Batterbury, M., Willoughby, C., Neal, T., Ahmad, S. & Kaye, S., 16 Feb 2019, In : BMJ Open Ophthalmology. 4, 1, p. 1-7 7 p., e000231.

    Research output: Contribution to journalArticle

    Open Access
  • 1 Citation (Scopus)