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  • Cromore Road, Coleraine Campus

    BT52 1SA Coleraine

    United Kingdom

  • 335 Citations
  • 12 h-Index
20142020

Research output per year

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Research Output

  • 335 Citations
  • 12 h-Index
  • 29 Article
  • 1 Conference contribution
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Article
2020
2019
Open Access
File
6 Citations (Scopus)
1 Downloads (Pure)
2018

Expression of Gastrin Family Peptides in Pancreatic Islets and Their Role in β-Cell Function and Survival

Khan, D., Vasu, S., Moffett, C., Irwin, N. & Flatt, P., 12 Jan 2018, In : Pancreas. 47, 2, p. 190-199

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)

Identification of Components in Frog Skin Secretions with Therapeutic Potential as Antidiabetic Agents

Conlon, JM., Moffett, C., Leprince, J. & Flatt, P., 24 Feb 2018, In : Methods in Molecular Biology. 1719, p. 319-333

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)

Oxytocin is present in islets and plays a role in beta-cell function and survival

Mohan, S., Khan, D., Moffett, C., Irwin, N. & Flatt, P., 3 Feb 2018, In : Peptides. 100, p. 260-268

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)
2017

Actions of PGLa-AM1 and its [A14K] and [A20K] analogues and their therapeutic potential as anti-diabetic agents

Owolabi, BO., Musalea, V., Ojo, OO., Moffett, C., McGahon, MK., Curtis, TM., Conlon, JM., Flatt, P. & Abdel-Wahab, YHA., 7 Apr 2017, In : Biochimie. 138, p. 1-12

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
27 Downloads (Pure)

Anti-diabetic actions of esculentin-2CHa(1–30) and its stable analogues in a diet-induced model of obesity-diabetes

Vasu, S., Ojo, O., Moffett, C., Conlon, JM., Flatt, P. & Abdel-Wahab, Y., 23 Aug 2017, In : Amino Acids. 49, 10, p. 1705-1717

Research output: Contribution to journalArticle

Open Access
7 Citations (Scopus)
Open Access
9 Citations (Scopus)

Esculentin-2CHa(1–30) and its analogues: stability and mechanisms of insulinotropic action

Vasu, S., McGahon, M., Moffett, C., Curtis, T., Conlon, JM., Abdel-Wahab, YHA. & Flatt, P., 1 Mar 2017, In : Journal of Endrocrinology. 232, 3, p. 423-435 13 p.

Research output: Contribution to journalArticle

Open Access
File
12 Citations (Scopus)
19 Downloads (Pure)
Open Access
File
20 Citations (Scopus)
10 Downloads (Pure)
Open Access
14 Citations (Scopus)

Metabolic and neuroprotective effects of dapagliflozin and liraglutide in diabetic mice

Millar, P., Pathak, N., Parthsarathy, V., Bjourson, AJ., O'Kane, M., Pathak, V., Moffett, C., Flatt, P. & Gault, V. A., 23 Jun 2017, (Accepted/In press) In : Journal of Endrocrinology. 234, 3, p. 255-267

Research output: Contribution to journalArticle

Open Access
19 Citations (Scopus)
2016

Beneficial metabolic actions of a stable GIP agonist following pre-treatment with a SGLT2 inhibitor in high fat fed diabetic mice.

Millar, PJ., Pathak, V., Moffett, C., Pathak, NM., Bjourson, AJ., OKane, MJ., Flatt, P. & Gault, V., 15 Jan 2016, In : Molecular and Cellular Endocrinology. 420, p. 37-45 8 p.

Research output: Contribution to journalArticle

Open Access
15 Citations (Scopus)
Open Access
File
4 Citations (Scopus)
12 Downloads (Pure)

Evaluation of the role of N-methyl-D-aspartate (NMDA) receptors in insulin secreting beta-cells

Patterson, S., Irwin, N., Gou-Parke, H., Moffett, C., Scullion, SM., Flatt, P. & McClenaghan, N., 15 Jan 2016, In : European Journal of Pharmacology. 771, p. 107-113

Research output: Contribution to journalArticle

Open Access
Open Access
File
35 Citations (Scopus)
58 Downloads (Pure)

Molecular mechanisms mediating the beneficial metabolic effects of [Arg4]tigerinin-1R in mice with diet-induced obesity and insulin resistance

Ojo, OO., Srinivasan, DK., Owolabi, BO., McGahon, MK., Moffett, C., Curtis, TM., Conlon, JM., Flatt, P. & Abdel-Wahab, Y., 1 Aug 2016, In : Biological Chemistry. 397, 8, p. 753-764

Research output: Contribution to journalArticle

Open Access
14 Citations (Scopus)
2015

Differential molecular and cellular responses of GLP-1 secreting L-cells and pancreatic alpha cells to glucotoxicity and lipotoxicity

Vasu, S., Moffett, C., McClenaghan, N. & Flatt, P., 1 Aug 2015, In : Experimental Cell Research. 336, (1), p. 100-108 9 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
Open Access
12 Citations (Scopus)

Evaluation of the role of N-methyl-d-aspartate (NMDA) receptors in insulin secreting beta-cells

Patterson, S., Irwin, N., Gou-Parke, H., Moffett, C., Scullion, SM., Flatt, P. & McClenaghan, N., 10 Dec 2015, In : European Journal of Pharmacology. 771, p. 107-113

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Functional GIP receptors play a major role in islet compensatory response to high fat feeding in mice

Moffett, C., Vasu, S. & Flatt, P., 14 Feb 2015, In : Biochim Biophys Acta. 1850, 6, p. 1206-1214

Research output: Contribution to journalArticle

Open Access
12 Citations (Scopus)

Pharmacological characterization and antidiabetic activity of a long-acting glucagon-like peptide-1 analogue conjugated to an antithrombin III-binding pentasaccharide

Patterson, S., de Kort, M., Irwin, N., Moffett, C., Dokter, WH., Bos, ES., Miltenburg, AM. & Flatt, P., 1 Aug 2015, In : Diabetes Obesity and Metabolism. 17, 8, p. 760-770 11 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
Open Access
16 Citations (Scopus)

Responses of GLP1-secreting L-cells to cytotoxicity resemble pancreatic β-cells but not α-cells.

Vasu, S., Moffett, C., McClenaghan, N. & Flatt, P., 1 Feb 2015, In : Journal of Molecular Endocrinology. 54, 1, p. 91-104

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)

Synthesis and Evaluation of a Series of Long-Acting Glucagon-Like Peptide-1 (GLP-1) Pentasaccharide Conjugates for the Treatment of Type 2 Diabetes

Irwin, N., Patterson, S., de Kort, M., Moffett, C., Wisse, JA., Dokter, WH., Bos, ES., Miltenburg, AM. & Flatt, P., 23 Jul 2015, In : ChemMedChem. 10, 8, p. 1424-1434 11 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2014

Incretin Receptor Null Mice Reveal Key Role of GLP-1 but Not GIP in Pancreatic Beta Cell Adaptation to Pregnancy.

Moffett, RC., Vasu, S., Thorens, B., Drucker, DJ., Flatt, P. & Moffett, C., 13 Jun 2014, In : PLoS ONE. 9, p. e96863

Research output: Contribution to journalArticle

Open Access
30 Citations (Scopus)

Role of Endogenous GLP-1 and GIP in Beta Cell Compensatory Responses to Insulin Resistance and Cellular Stress

Vasu, S., Moffett, C., Thorens, B. & Flatt, P., 26 Jun 2014, In : PLoS ONE. 9, 6, p. 1-9 9 p., e101005.

Research output: Contribution to journalArticle

Open Access
42 Citations (Scopus)