• Cromore Road, Coleraine Campus

    BT52 1SA Coleraine

    United Kingdom

  • 1120 Citations
  • 19 h-Index
20082020
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Research Output 2008 2020

  • 1120 Citations
  • 19 h-Index
  • 39 Article
  • 1 Chapter
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Article
2020
Rose Bengal
Photochemotherapy
Melanoma
Peptides
Reactive Oxygen Species
2019
5 Citations (Scopus)
Rose Bengal
Microbubbles
Paclitaxel
Doxorubicin
Breast Neoplasms
2018
3 Citations (Scopus)
Open Access
Drug Monitoring
Saliva
Newborn Infant
Primidone
Busulfan
3 Citations (Scopus)

Electroneutral polymersomes for combined cancer chemotherapy

Aibani, N., Nesbitt, H., Marino, N., Jurek, J., Martin, C., Di Bari, I., Sheng, Y., Logan, K., Hawthorne, S., McHale, A. P., Callan, J. F. & Callan, B., 15 Oct 2018, In : Acta Biomaterialia. 80, p. 327-340

Research output: Contribution to journalArticle

Open Access
File
Chemotherapy
Tumors
Drug Therapy
Pharmaceutical Preparations
Neoplasms
12 Citations (Scopus)

Gemcitabine loaded microbubbles for targeted chemo-sonodynamic therapy of pancreatic cancer

Nesbitt, H., Sheng, Y., Kamila, S., Logan, K., Thomas, K., Callan, B., Taylor, M., Love, M., O'Rourke, D., Kelly, P., Beguin, E., Stride, E., McHale, AP. & Callan, J., 10 Jun 2018, In : Journal of Controlled Release. 279, p. 8-16 9 p.

Research output: Contribution to journalArticle

Open Access
gemcitabine
Microbubbles
Pancreatic Neoplasms
SCID Mice
Heterografts
3 Citations (Scopus)
Open Access
File
Extracellular Fluid
Glucose
Equipment and Supplies
Blood Glucose Self-Monitoring
Hyperglycemia
2017
10 Citations (Scopus)

A versatile, stimulus-responsive nanoparticle-based platform for use in both sonodynamic and photodynamic cancer therapy

Nomikou, N., Curtis, K., McEwan, C., O'Hagan, B., Callan, B., Callan, J. & McHale, AP., 28 Feb 2017, In : Acta Biomaterialia. 49, p. 414-421 8 p.

Research output: Contribution to journalArticle

Open Access
File
Photochemotherapy
Nanoparticles
Tumors
Ultrasonics
Indocyanine Green
39 Citations (Scopus)

Iodinated Cyanine Dyes: A New Class of Sensitisers for use in NIR Activated Photodynamic Therapy (PDT)

Callan, J., Atchison, J., Kamila, S., Logan, K., Nicholas, D., Fowley, C., Davis, J., Callan, B. & McHale, A., 18 Jan 2017, In : Chemical Communications. 53, 12, p. 2009-2012

Research output: Contribution to journalArticle

Open Access
File
Photodynamic therapy
Tumors
Coloring Agents
Dyes
Cells
8 Citations (Scopus)

Magnetically Responsive Microbubbles as Delivery Vehicles for Targeted Sonodynamic and Antimetabolite Therapy of Pancreatic Cancer

Sheng, Y., Beguin, E., Nesbitt, H., Kamila, S., Owen, J., Barnsley, L., Callan, B., O'Kane, C., Nomikou, N., Hamoudi, R., Taylor, M. A., Love, M., Kelly, P., O'Rourke, D., Stride, E., McHale, AP. & Callan, J., 28 Sep 2017, In : Journal of Controlled Release. 262, p. 192-200 9 p.

Research output: Contribution to journalArticle

Open Access
Antimetabolites
Microbubbles
Pancreatic Neoplasms
Fluorouracil
Rose Bengal
16 Citations (Scopus)

Oxygen Generating Nanoparticles for Improved Photodynamic Therapy of Hypoxic Tumours.

Callan, J., Sheng, Y., Nesbitt, H., Callan, B. & McHale, AP., 8 Sep 2017, In : Journal of Controlled Release. 264, p. 333-340

Research output: Contribution to journalArticle

Open Access
Photochemotherapy
Nanoparticles
Oxygen
Polymers
Neoplasms
7 Citations (Scopus)

The integration of triggered drug delivery with real time quantification using FRET; creating a super ‘smart’ drug delivery system.

Aibani, N., Fontoura da Costa, P., Masterson, J., Marino, N., Raymo, F. M., Callan, J. F. & Callan, B., 18 Aug 2017, In : Journal of Controlled Release. 263

Research output: Contribution to journalArticle

Open Access
File
Energy Transfer
Drug Delivery Systems
Pharmaceutical Preparations
Light
Fluorescence
2016
4 Citations (Scopus)

Cholesteryl to improve the cellular uptake of Polymersomes within HeLa cells

Martin, C., Marino, N., Curran, C., McHale, AP., Callan, J. F. & Callan, B., 10 Sep 2016, In : International Journal of Pharmaceutics. 511, 1, p. 570-578

Research output: Contribution to journalArticle

Open Access
File
Drug Delivery Systems
HeLa Cells
Polymers
Endocytosis
Dextrans
42 Citations (Scopus)

Combined sonodynamic and antimetabolite therapy for the improved treatment of pancreatic cancer using oxygen loaded microbubbles as a delivery vehicle

McEwan, C., Kamila, S., Owen, J., Nesbitt, H., Callan, B., Borden, M., Nomikou, N., Hamoudi, R. A., Taylor, M. A., Stride, E., McHale, AP. & Callan, J., 29 Feb 2016, In : Biomaterials. 80, p. 20-32 13 p.

Research output: Contribution to journalArticle

Antimetabolites
Microbubbles
Pancreatic Neoplasms
Tumors
Oxygen
16 Citations (Scopus)

Recent advances in amphiphilic polymers for simultaneous delivery of hydrophobic and hydrophilic drugs

Martin, C., Aibani, N., Callan, J. & Callan, B., Jan 2016, In : Therapeutic Delivery. 7, 1, p. 15-31

Research output: Contribution to journalArticle

Open Access
Nanocapsules
Nanomedicine
Micelles
Drug Delivery Systems
Polymers
52 Citations (Scopus)

Sonodynamic Therapy: Concept, Mechanism and Application to Cancer Treatment

McHale, AP., Callan, J., Nomikou, N., Fowley, C. & Callan, B., 2016, In : Advances in Experimental Medicine and Biology. 880, p. 429-450

Research output: Contribution to journalArticle

Open Access
2015
4 Citations (Scopus)

A charge neutral, size tuneable polymersome capable of high biological encapsulation efficiency and cell permeation.

Martin, C., Dolmazon, E., Moylan, K., Fowley, C., McHale, AP., Callan, J. F. & Callan, B., 2015, In : International Journal of Pharmaceutics. 481, p. 1-8

Research output: Contribution to journalArticle

Open Access
File
Encapsulation
Permeation
Dextrans
Fluorescein-5-isothiocyanate
Dynamic light scattering
6 Citations (Scopus)

A new three-component formulation for the efficient whitening of teeth (Carbamide Plus)

Hyland, B., McDonald, A., Lewis, N., Tredwin, C., Petrie, A., Hall, S., Todd, C., McCaughan, B. & Callan, J., 2015, In : Clinical Oral Investigations. 19, 6, p. 1395-1404

Research output: Contribution to journalArticle

Open Access
Tooth Bleaching
Urea
Hydrogen Peroxide
Magnetic Resonance Spectroscopy
Controlled Clinical Trials

Energy-Transfer Schemes To Probe Fluorescent Nanocarriers and Their Emissive Cargo

Callan, J., Callan, B., Thapaliya, E. R., Fowley, C., Raymo, F., Tang, SC. & Zhang, Y., 14 Aug 2015, (Accepted/In press) In : Langmuir. 31, p. 9557-9565

Research output: Contribution to journalArticle

Fluorescent Dyes
Energy transfer
Micelles
Chromophores
Cells
14 Citations (Scopus)
Open Access
File
Photodynamic therapy
Bearings (structural)
Modulation
Heterografts
Tumors
10 Citations (Scopus)

Supramolecular nanoreactors for intracellular singlet-oxygen sensitization

Swaminathan, S., Fowley, C., Thapaliya, E. R., McCaughan, B., Tang, S., Fraix, A., Captain, B., Sortino, S., Callan, J. & Raymo, F. M., 28 Jul 2015, In : Nanoscale. 7, 33, p. 14071-14079

Research output: Contribution to journalArticle

Open Access
Nanoreactors
Singlet Oxygen
Chromophores
Energy transfer
Containers
2014
16 Citations (Scopus)

A ratiometric fluorescent hydrogel sensor for zinc(II) based on a two fluorophore approach

Hamilton, G., Fullerton, L., McCaughan, B., Donnelly, R. F. & Callan, J., 2014, In : New Journal of Chemistry. 38, 7, p. 2823-2830

Research output: Contribution to journalArticle

Open Access
Fluorophores
Hydrogel
Zinc
Sensors
Dilution
45 Citations (Scopus)

Carbon quantum dot-NO photoreleaser nanohybrids for two-photon phototherapy of hypoxic tumors

Fowley, C., McHale, AP., McCaughan, B., Fraix, A., Sortino, S. & Callan, J., 5 Nov 2014, In : Chemical Communications. 51, 1, p. 81-84

Research output: Contribution to journalArticle

Open Access
Semiconductor quantum dots
Tumors
Bearings (structural)
Carbon
Photons
30 Citations (Scopus)

Intracellular Guest Exchange between Dynamic Supramolecular Hosts

Swaminathan, S., Fowley, C., McCaughan, B., Cusido, J., Callan, J. & Raymo, F. M., 4 Jun 2014, In : Journal of the American Chemical Society. 136, 22, p. 7907-7913 7 p.

Research output: Contribution to journalArticle

Nanoparticles
Energy Transfer
Energy transfer
Containers
Intracellular Space
34 Citations (Scopus)

Polymeric microbubbles as delivery vehicles for sensitizers in sonodynamic therapy

McEwan, C., Fowley, C., Nomikou, N., McCaughan, B., McHale, AP. & Callan, J., 2014, In : Langmuir. 30, 49, p. 14926-14930

Research output: Contribution to journalArticle

Open Access
Microbubbles
Lipids
Rose Bengal
Therapeutics
Tumor Burden
2012
47 Citations (Scopus)

Highly luminescent biocompatible carbon quantum dots by encapsulation with an amphiphilic polymer

Fowley, C., McCaughan, B., Devlin, A., Yildiz, I., Raymo, F. M. & Callan, J. F., 2012, In : Chemical Communications. 48, 75, p. 9361-9363

Research output: Contribution to journalArticle

Open Access
Cell membranes
Encapsulation
Semiconductor quantum dots
Polymers
Carbon
34 Citations (Scopus)

Microbubble-sonosensitiser conjugates as therapeutics in sonodynamic therapy

Nomikou, N., Fowley, C., Byrne, N. M., McCaughan, B., MCHALE, AP. & Callan, J. F., 2012, In : Chemical Communications. 48, 67, p. 8332-8334

Research output: Contribution to journalArticle

Open Access
Rose Bengal
Singlet Oxygen
Cytotoxicity
Tumors
Cells
43 Citations (Scopus)

Photoinduced Enhancement in the Luminescence of Hydrophilic Quantum Dots Coated with Photocleavable Ligands

Impellizzeri, S., Callan, B., Callan, J. F. & Raymo, F. M., Feb 2012, In : JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 134, 4, p. 2276-2283

Research output: Contribution to journalArticle

Open Access
Semiconductor quantum dots
Luminescence
Ligands
Nanoparticles
Photooxidation
41 Citations (Scopus)

The Effects of Ultrasound and Light on Indocyanine-Green-Treated Tumour Cells and Tissues

Nomikou, N., Sterrett, C., Arthur, C., McCaughan, B., Callan, JF. & MCHALE, AP., 1 Aug 2012, In : ChemMedChem. 7, 8, p. 1465-1471

Research output: Contribution to journalArticle

Open Access
Indocyanine Green
Light
Neoplasms
Photochemotherapy
Therapeutics
43 Citations (Scopus)
Open Access
Photodynamic therapy
Photosensitizing Agents
Semiconductor quantum dots
Photons
Water
2011
22 Citations (Scopus)

Enhanced ROS production and cell death through combined photo- and sono-activation of conventional photosensitising drugs.

McCaughan, B., Rouanet, C., Fowley, C., Nomikou, N., McHale, A. & Callan, J., 1 Oct 2011, In : Bioorganic and Medicinal Chemistry Letters. 21, 19, p. 5750-5752

Research output: Contribution to journalArticle

Open Access
Cell death
Reactive Oxygen Species
Cell Death
Ultrasonics
Chemical activation
114 Citations (Scopus)

Supramolecular Strategies To Construct Biocompatible and Photoswitchable Fluorescent Assemblies

Yildiz, I., Impellizzeri, S., Deniz, E., Callan, B., Callan, J. & Raymo, F. M., Feb 2011, In : JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 133, 4, p. 871-879

Research output: Contribution to journalArticle

Open Access
Boron
Lighting
Fluorescence
Methacrylates
Fluorophores
2010
33 Citations (Scopus)

AND molecular logic using semiconductor quantum dots

Kaur, N., Singh, N., Callan, B. & Callan, J., Jan 2010, In : SENSORS AND ACTUATORS B-CHEMICAL. 144, 1, p. 88-91

Research output: Contribution to journalArticle

Open Access
Semiconductor quantum dots
Ions
Protons
Sodium
Fluorescence
72 Citations (Scopus)

Hydrophilic CdSe-ZnS Core-Shell Quantum Dots with Reactive Functional Groups on Their Surface

Yildiz, I., Deniz, E., Callan, B., Cruickshank, S. F., Callan, J. & Raymo, F. M., Jul 2010, In : Langmuir. 26, 13, p. 11503-11511

Research output: Contribution to journalArticle

Open Access
Functional groups
Semiconductor quantum dots
Carboxylic Acids
Nanoparticles
Sulfhydryl Compounds
56 Citations (Scopus)

Ratiometric fluorescent detection of Cu(II) in semi-aqueous solution using a two-fluorophore approach

Singh, N., Kaur, N., Callan, B. & Callan, J., Jun 2010, 51, 26, p. 3385-3387

Research output: Contribution to journalArticle

Open Access
Naphthalimides
Fluorophores
Schiff Bases
HEPES
Isomerization

Supramolecular Strategies To Construct Biocompatible andPhotoswitchable Fluorescent Assemblies

Yildiz, I., Impellizzeri, S., Deniz, E., McCaughan, B., Callan, J. & Raymo, F., 20 Aug 2010, In : JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 133, p. 871-879

Research output: Contribution to journalArticle

Open Access
Lighting
Fluorescence
Boron
Ethylene Glycol
Methacrylates
2009
80 Citations (Scopus)

Biocompatible CdSe-ZnS Core-Shell Quantum Dots Coated with Hydrophilic Polythiols

Yildiz, I., McCaughan, B., Cruickshank, S. F., Callan, J. F. & Raymo, F. M., Jun 2009, In : Langmuir. 25, 12, p. 7090-7096

Research output: Contribution to journalArticle

Open Access
Semiconductor quantum dots
Ligands
Polyethylene glycols
Nanoparticles
Sulfhydryl Compounds
2008
68 Citations (Scopus)
Open Access
Hydrobromic Acid
Semiconductor quantum dots
Anions
Coloring Agents
Fluorophores
16 Citations (Scopus)

A potential new prodrug for the treatment of cystinosis:Design, synthesis and in-vitro evaluation

McCaughan, B., Kay, G., Knott, R. M. & Cairns, D., 12 Jan 2008, In : Bioorganic & Medicinal Chemistry Letters. 18, p. 1716-1719

Research output: Contribution to journalArticle

Open Access
Cystinosis
Cystine
Prodrugs
Patient Compliance
Cysteamine