Research Output

2020

Albumin Nano-Encapsulation of Piceatannol Enhances Its Anticancer Potential in Colon Cancer Via Downregulation of Nuclear p65 and HIF-1α

A.a. Aljabali, Bakshi, H., L. Hakkim, A. Haggag, M. Al-batanyeh, S. Al Zoubi, Al-trad, B., Nasef, M., Satija, S., Mehta, P., Pabreja, K., Mishra, V., Khan, M., Abobaker, Azzouz, Dureja, H., Pabari, Dardouri, Kesharwani, P., Gupta, S. & 11 others, Dhar Shukla, Prasher, B. Charbe, Negi, S., N. Kapoor, Chellappan, D. K., Webba da Silva, M., Thompson, J., Dua, H. S., McCarron, P. & Tambuwala, M., 1 Jan 2020, In : Cancers. 12, 1, p. 113 113.

Research output: Contribution to journalArticle

Open Access
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1 Citation (Scopus)

An intraocular pressure polygenic risk score stratifies multiple primary open angle glaucoma parameters including treatment intensity

Qassim, A., Souzeau, E., Siggs, O. M., Hassall, M. M., Han, X., Griffiths, H. L., Frost, N. A., Vallabh, N. A., Kirwan, J. F., Menon, G., Cree, A. J., Galanopoulos, A., Agar, A., Healey, P. R., Graham, S. L., Landers, J., Casson, R. J., Gharahkhani, P., Willoughby, C., Hewitt, A. W. & 3 others, Lotery, A. J., MacGregor, S. & Craig, J. E., 7 Jan 2020, In : OPHTHALMOLOGY.

Research output: Contribution to journalArticle

An investigation of the vitamin D Knowledge, Attitudes and Practice of UK practising doctors and nurses: the D-KAP study

Fallon, E. L., Lanham-New, S. A., Williams, P. & Ray, S., 22 Jan 2020, In : PROCEEDINGS OF THE NUTRITION SOCIETY. 79, OCE1, p. E20-E20 E20.

Research output: Contribution to journalComment/debate

Assessing the Oxidative Degradation of N-methyl Pyrrolidone (NMP) in Microelectronic Fabrication Processes by using a Multi-platform Analytical Approach

Cobice, D., Dobbin, S., Lennon, G., Willox, S., Ramdas, R., Funston, S., Klun, M., Pieh, R. & Fairlie, S., 21 Jan 2020, (Accepted/In press) In : Journal of Analytical Methods in Chemistry.

Research output: Contribution to journalArticle

Open Access
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Association of Audiometric Measures with plasma long chain polyunsaturated fatty acids in a high-fish eating population: The Seychelles Child Development Study

Orlando, M., Dziorny, A., Love, T., Harrington, D., Shamlaye, C., Watson, G., van Wijngaarden, E., Zareba, G., Davidson, P., Mulhern, M. S., McSorley, E. M., Yeates, A. J., Strain, S. & Myers, G., 31 Mar 2020, In : Neurotoxicology. 77, p. 137-144 8 p.

Research output: Contribution to journalArticle

Associations between maternal inflammation during pregnancy and infant birth outcomes in the Seychelles Child Development Study: Maternal inflammation and birth outcomes

Yeates, A. J., McSorley, E. M., Mulhern, M. S., Spence, T., Crowe, W., Grzesik, K., Thurston, S., Watson, G., Myers, G., Davidson, P., Shamlaye, C., Edwin, V. W. & Strain, S., 1 Feb 2020, In : Journal of Reproductive Immunology. 137, 6 p., 102623.

Research output: Contribution to journalArticle

Open Access
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Automated Pupillometry using a Prototype Binocular Optical Coherence Tomography System: Automated, quantitative, pupillometry using Binocular OCT

Chopra, R., Mulholland, P., Petzold, A., Ogunbowale, L., Gazzard, G., Bremner, F., Anderson, RS. & Keane, P. A., 13 Feb 2020, (Accepted/In press) In : American Journal of Ophthalmology.

Research output: Contribution to journalArticle

Biochemical mechanisms of aggregation in TGFBI-linked corneal dystrophies.

Nielsen, N. S., Toftgaard Poulsen, E., Lukassen, M. V., Chao Shern, C., Hage Mogensen, E., Weberskov, C. E., Dedionisio, L., Schauser, L., Moore, T. C. B., Otzen, D. E., Hjortdal, J. & Enghild, J. J., 29 Jan 2020, In : Progress in Retinal and Eye Research. 100843.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Biodegradation potential of crude petroleum by hydrocarbonoclastic bacteria isolated from Soummam wadi sediment and chemical-biological proprieties of their biosurfactants

Yalaoui-Guella, D., Fella-Temzi, S., Djafri-Dib, S., Madani, K., Banat, I. & Brahmi, F., 31 Jan 2020, In : Journal of Petroleum Science and Engineering. 184, p. 1-7 7 p., 106554.

Research output: Contribution to journalArticle

BloodTracKR- a device which connects patients to the clinic

Gibson, D., Jan 2020, 2 p.

Research output: Other contribution

Open Access
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Calcium l‐methylfolate as a source of folate added for nutritional purposes to infant and follow‐on formula, baby food and processed cereal‐based food

Turck, D., Castenmiller, J., De Henauw, S., Hirsch‐Ernst, K. I., Kearney, J., Maciuk, A., Mangelsdorf, I., McArdle, H. J., Naska, A., Pelaez, C., Pentieva, K., Siani, A., Thies, F., Tsabouri, S., Vinceti, M., Cubadda, F., Engel, K-H., Frenzel, T., Heinonen, M., Marchelli, R. & 8 others, Neuhauser-Berthold, M., Poulsen, M., Sanz, Y., Schlatter, J. R., van Loveren, H., Bernasconi, G., Germini, A. & Knutsen, H. K., 17 Jan 2020, In : EFSA Journal. 18, 1, p. 5947 18 p., e05947.

Research output: Contribution to journalArticle

Open Access
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Color discrimination assessment in patients with hypothyroidism using the Farnsworth-Munsell 100 hue test.

Racheva, K., Totev, T., Natchev, E., Bocheva, N., Beirne, R. & Vidinova-Zlatkova, M., 10 Jan 2020, (Accepted/In press) In : Journal of the Optical Society of America A.

Research output: Contribution to journalArticle

Comprehensive transcriptomic analysis of papillary thyroid cancer: potential biomarkers associated with tumor progression

Hosseinkhan, N., Honardoost, M., Blighe, K., Moore, T. C. B. & Khamseh, M. E., 21 Jan 2020, In : Journal of Endocrinological Investigation.

Research output: Contribution to journalArticle

Computational Neurology: Computational Modeling Approaches in Dementia

Wong-Lin, K., Sanchez Bornot, J., McCombe, N., Kaur, D., McClean, P., Zou, X., Youssofzadeh, V., Ding, X., Bucholc, M., Yang, S., Prasad, G., Coyle, D., Maguire, L., Wang, H. . HY., Wang, H., Atiya, N. & Joshi, A., 7 Mar 2020, (Accepted/In press) Systems Medicine: Integrative, Qualitative and Computational Approaches. Wolkenhauer, O. (ed.). Elsevier Inc., 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Computational Time Series Analysis of Patient Referrals to a Primary Percutaneous Coronary Intervention Service

Iftikhar, A., Bond, RR., McGilligan, V. E., Leslie, S. J., McShane, A., Knoery, C., Rjoob, K. & Peace, A., 24 Jan 2020, In : Health Informatics Journal. 15 p.

Research output: Contribution to journalArticle

Open Access
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CRISPR/Cas9 gene editing demonstrates metabolic importance of GPR55 in the modulation of GIP release and pancreatic beta cell function.

McCloskey, A. G., Miskelly, M. G., Moore, T. C. B., Nesbit, M. A., Christie, K., Owolabi, A., Flatt, PR. & McKillop, A., 31 Mar 2020, In : Peptides. 125, 170251.

Research output: Contribution to journalReview article

Enhanced expression of beta cell Ca(v)3.1 channels impairs insulin release and glucose homeostasis

Yu, J., Shi, Y., Zhao, K., Yang, G., Yu, L., Li, Y., Andersson, E., Ämmälä, C., Yang, S. & Berggren, P., 7 Jan 2020, In : Proceedings of the National Academy of Sciences. 117, 1, p. 448-453 6 p.

Research output: Contribution to journalArticle

Enteroendocrine K-cells exert complementary effects to control bone quality and mass in mice

Gobron, B., Bouvard, B., Vyavahare, S., Blom, L. V. V., Pedersen, K. K., Windeløv, J. A., Boer, G. A., Harada, N., Zhang, S., Shimazu-Kuwahara, S., Wice, B., Inagaki, N., Legrand, E., Flatt, PR., Chappard., D., Hartmann, B., Holst, J. J., Rosenkilde, M. M., Irwin, N. & Mabilleau, G., 4 Mar 2020, (Accepted/In press) In : Journal of Bone and Mineral Research. xx, p. xx

Research output: Contribution to journalArticle

Estimation of ocular axial length from conventional optometric measures

Morgan, P., McCullough, S. & Saunders, K. J., 29 Feb 2020, In : Contact Lens and Anterior Eye. 43, 1, p. 18-20 3 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Eyewear for Rugby Union: wearer characteristics and experience with Rugby Goggles

Little, J-A., Eckert, F., Douglas, M. & Barrett, B., 27 Jan 2020, In : International Journal of Sports Medicine.

Research output: Contribution to journalArticle

Open Access

GIP renaissance

Flatt, PR. & Conlon, JM., 23 Jan 2020, (Accepted/In press) In : Peptides. xx, p. xx xx.

Research output: Contribution to journalArticle

Identification and characterisation of peptides from a boarfish (Capros aper) protein hydrolysate displaying in vitro dipeptidyl peptidase-IV (DPP-IV) inhibitory and insulinotropic activity

Harnedy-Rothwell, PA., McLaughlin, C., O’Keeffe, MB., Le Gouic, AV., Allsopp, P. J., McSorley, E. M., Sharkey, S., Whooley, J., McGovern, B., O'Harte, F. & Fitzgerald, RJ., 21 Jan 2020, In : Food Research International. 131, 108989.

Research output: Contribution to journalArticle

Improving computational skills of personalised Medicine students through positive pedagogy

Shukla, P., 20 Feb 2020, Improving computational skills of personalised Medicine students through positive pedagogy.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Open Access

Isolation and characterization of cytotoxic and insulin-releasing components from the venom of the black-necked spitting cobra Naja nigricollis (Elapidae)

Conlon, JM., Attoub, S., Musale, V., Leprince, J., Casewell, N., Sanze, L. & Calvete, J., 9 Mar 2020, (Accepted/In press) In : Toxicon. p. xxx

Research output: Contribution to journalArticle

Open Access
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Liraglutide and sitagliptin counter beta- to alpha-cell transdifferentiation in diabetes

Tanday, N., Flatt, PR., Irwin, N. & Moffett, C., 23 Jan 2020, (Accepted/In press) In : Journal of Endrocrinology. xx, xx, p. xx

Research output: Contribution to journalArticle

MenaQ7 (R) and maintenance of the elastic properties of the arteries: evaluation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006

Turck, D., Castenmiller, J., De Henauw, Hirsch‐Ernst, Kearney, Knutsen, Maciuk, Mangelsdorf, McArdle, Naska, Pelaez, Pentieva, K., Siani, Thies, Tsabouri, Vinceti & Bresson, 31 Jan 2020, In : EFSA Journal. 18, 1, 10 p., e05949.

Research output: Contribution to journalArticle

Open Access
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Methylmercury and long chain polyunsaturated fatty acids are associated with immune dysregulation in young adults from the Seychelles child development study.

McSorley, E. M., van Wijngaarden, E., Yeates, A. J., Spence, T., Mulhern, M. S., Harrington, D., Thurston, S., Love, T., Jusko, T., Allsopp, P. J., Conway, M., Davidson, P., Myers, G., Watson, G., Shamlaye, C. & Strain, S., 1 Apr 2020, In : Environmental Research. 183, 8 p., 109072.

Research output: Contribution to journalArticle

Open Access
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Minerals and Trace Elements

Strain, S., Yeates, A. J. & Cashman, K., 16 Jan 2020, Introduction to Human Nutrition Third Edition. Lanham-New, S., Hill, T., Gallagher, A. & Vorster, H. (eds.). 3rd ed. Wiley-Blackwell Publishing Ltd, p. 280-338 (The Nutrition Society Textbook Series).

Research output: Chapter in Book/Report/Conference proceedingChapter

miR-210 is Induced by Hypoxia and Regulates Neural Cell Adhesion Molecule in Prostate Cells

Angel, Z., Lynch, S. M., Nesbitt, H., McKenna, M. M., Walsh, CP. & McKenna, D. J., 24 Jan 2020, In : Journal of Cellular Physiology. 10 p.

Research output: Contribution to journalArticle

Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression

Craig, J. E., Han, X., Qassim, A., Hassall, M., Cooke Bailey, J. N., Kinzy, T. G., Khawaja, A. P., An, J., Marshall, H., Gharahkhani, P., Igo, R. P., Graham, S. L., Healey, P. R., Ong, J., Zhou, T., Siggs, O., Law, M. H., Souzeau, E., Ridge, B., Hysi, P. G. & 39 others, Burdon, K. P., Mills, R. A., Landers, J., Ruddle, J. B., Agar, A., Galanopoulos, A., White, A. J. R., Willoughby, C. E., Andrew, N. H., Best, S., Vincent, A. L., Goldberg, I., Radford-smith, G., Martin, N. G., Montgomery, G. W., Vitart, V., Hoehn, R., Wojciechowski, R., Jonas, J. B., Aung, T., Pasquale, L. R., Cree, A. J., Sivaprasad, S., Vallabh, N. A., Viswanathan, A. C., Pasutto, F., Haines, J. L., Klaver, C. C. W., Van Duijn, C. M., Casson, R. J., Foster, P. J., Khaw, P. T., Hammond, C. J., Mackey, D. A., Mitchell, P., Lotery, A. J., Wiggs, J. L., Hewitt, A. W. & Macgregor, S., 1 Feb 2020, In : Nature Genetics. 52, 2, p. 160-166 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
Open Access
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Pharmacological potential of novel agonists for FFAR4 on islet and enteroendocrine cell function and glucose homeostasis

Mc Closkey, A., Miskelly, M., Flatt, PR. & McKillop, A., 15 Jan 2020, In : European Journal of Pharmaceutical Sciences. 142, 10 p., 105104.

Research output: Contribution to journalArticle

Porphyrin Production and Regulation in Cutaneous Propionibacteria

Barnard, E., Johnson, T., Ngo, T., Arora, U., Leuterio, G., Mc Dowell, A. & Li, H., 15 Jan 2020, In : mSphere. 5, 1, p. 1-10 10 p., e00793-19.

Research output: Contribution to journalArticle

Open Access
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Potential Use of Microbial Surfactant in Microemulsion Drug Delivery System: A Systematic Review

Ohadi, M., Shahravan, A., Dehghannoudeh, N., Eslaminejad, T., Banat, I. & Dehaghannoudeh, G., 5 Feb 2020, In : Drug Design, Development and Therapy. 14, p. 541-550 10 p.

Research output: Contribution to journalArticle

Open Access
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Safety of selenium‐enriched biomass of Yarrowia lipolytica as a novel food pursuant to Regulation (EU) 2015/2283

Turck, Castenmiller, De Henauw, Hirsch‐Ernst, Kearney, Maciuk, Mangelsdorf, McArdle, Naska, Pelaez, Pentieva, K., Siani, Thies, Tsabouri, Vinceti, Cubadda, Engel, Frenzel, Heinonen, Marchelli & 7 others, Neuhauser-Berthold, Poulsen, Sanz, Schlatter, van Loveren, Ackerl & Knutsen, 31 Jan 2020, In : EFSA Journal. 18, 1, 13 p., e05992.

Research output: Contribution to journalArticle

Open Access
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Should formula for infants provide arachidonic acid along with DHA? A position paper of the European Academy of Paediatrics and the Child Health Foundation

Koletzko, B., Bergmann, K., Brenna, T., Calder, P., Campoy, C., Clandinin, T., Colombo, J., Daly, M., Decsi, T., Demmelmair, H., Domellof, M., FildlerMis, N., Gonzalez-Casanova, I., can Goudoever, J., Hadjipanayis, A., Hernell, O., Lapillonne, A., Mader, S., Martin, C., Matthaus, V. & 6 others, Ramakrishan, U., Smuts, C., Strain, S. J. J., Tanjung, C., Tounian, P. & Carlson, S., 10 Jan 2020, In : American Journal of Clinical Nutrition. 111, 1, p. 10-16 7 p.

Research output: Contribution to journalSpecial issue

4 Citations (Scopus)

Studies of mice deleted for Sox3 and uc482: relevance to X-linked hypoparathyroidism

Gaynor, K. U., Grigorieva, I. V., Mirczuk, S. M., Piret, S. E., Kooblall, K. G., Stevenson, M., Rizzoti, K., Bowl, M. R., Nesbit, M. A., Christie, P. T., Fraser, W. D., Hough, T., Whyte, M. P., Lovell-Badge, R. & Thakker, R. V., 29 Feb 2020, In : Endocrine Connections. 9, 2, p. 173-186 14 p.

Research output: Contribution to journalArticle

Open Access
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The effect of sophorolipids against microbial biofilms on medical-grade silicone

Ceresa, C., Fracchia, L., Williams, M., Banat, I. & Diaz De Rienzo, MA., 10 Feb 2020, In : Journal of Biotechnology. 309, p. 34-43 10 p.

Research output: Contribution to journalArticle

The NNEdPro Global Centre for Nutrition and Health: A Consolidated Review of Global Efforts Towards Medical and Healthcare-Related Nutrition Education

Black, M. M. (ed.), Delichatsios, H. K. (ed.), Story, M. T. (ed.) & Ray, S., 2020, Nutrition Education: Strategies for Improving Nutrition and Healthy Eating in Individuals and Communities. Vol. 92. p. 143-150 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Ψ-xenin-6 enhances sitagliptin effectiveness, but does not improve glucose tolerance

Craig, S., Gault, V. A., Hamscher, G. & Irwin, N., 4 Mar 2020, (Accepted/In press) In : Journal of Endrocrinology. xx, p. xx

Research output: Contribution to journalArticle

‘What’s the Point?’ - Understanding why people with Type 2 diabetes decline structured education

Findlay-White, F., Slevin, M., Carey, M. & Coates, V., 2 Mar 2020, In : Clinical Diabetes. 38, 1, p. 1-10 10 p.

Research output: Contribution to journalArticle

Open Access
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